{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-6YJAQEZN/b676e47c-100c-4456-91fc-a9cee75e6816/PDF","dcterms:extent":"1637 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-6YJAQEZN/55111a69-9ac4-44f0-ad2b-5f7b93c29976/TEXT","dcterms:extent":"0 KB"}],"edm:TimeSpan":{"@rdf:about":"2005-2025","edm:begin":{"@xml:lang":"en","#text":"2005"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-6YJAQEZN","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-8ER5ZBJN"},{"@xml:lang":"sl","#text":"Farmacevtski vestnik"}],"dcterms:issued":"2021","dc:creator":["Ahlin Grabnar, Pegi","Bjelošević, Maja"],"dc:format":[{"@xml:lang":"sl","#text":"številka:3"},{"@xml:lang":"sl","#text":"letnik:72"},{"@xml:lang":"sl","#text":"str. 159-166"}],"dc:identifier":["ISSN:0014-8229","COBISSID_HOST:70291971","URN:URN:NBN:SI:doc-6YJAQEZN"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"dc:subject":[{"@xml:lang":"sl","#text":"agresivno sušenje"},{"@xml:lang":"sl","#text":"Biološka zdravila"},{"@xml:lang":"sl","#text":"liofilizacija"},{"@xml:lang":"sl","#text":"optimizacija liofilizacije"},{"@xml:lang":"sl","#text":"Sušenje"},{"@xml:lang":"sl","#text":"sušenje z zamrzovanjem"}],"dcterms:temporal":{"@rdf:resource":"2005-2025"},"dc:title":{"@xml:lang":"sl","#text":"Pomen liofilizacije v farmaciji| Importance of lyophilisation in pharmacy|"},"dc:description":[{"@xml:lang":"sl","#text":"Today, lyophilisation is the method of choice for the preparation of stable formulations with protein active ingredients, and its use and deeper understanding have become increasingly important in terms of preparation of new, patient-friendly dosage forms. In line with the intensive increase in the number of new biologic and biosimilar drugs, the pharmaceutical industry is increasingly focusing on the development and optimisation of the lyophilisation process, with the aim of providing quality, safe and effective drugs. The purpose of the article is to present the process of lyophilisation and innovations in this field, and to highlight its importance in the field of pharmacy"},{"@xml:lang":"sl","#text":"Liofilizacija je danes metoda izbora za pripravo stabilnih formulacij s proteinskimi zdravilnimi učinkovinami, njena uporaba in globlje razumevanje pa postajata čedalje bolj pomembna tudi z vidika priprave novih, pacientu prijaznih farmacevtskih oblik. Skladno z intenzivnim povečanjem števila novih bioloških in biološko podobnih zdravil se farmacevtska industrija vse bolj usmerja k razvoju in optimizaciji procesa liofilizacije, z namenom zagotavljanja kakovostnih, varnih in učinkovitih zdravil. Namen članka je predstaviti proces liofilizacije in novosti na tem področju ter izpostaviti njegovo pomembnost na področju farmacije"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-6YJAQEZN","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-6YJAQEZN"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-6YJAQEZN/b676e47c-100c-4456-91fc-a9cee75e6816/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-6YJAQEZN/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-6YJAQEZN"}}}}