{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-52I46PY6/43c2a934-5722-41a8-a654-f5c4df6bffe0/PDF","dcterms:extent":"14127 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-52I46PY6/6b734746-d9ca-4114-8e19-449d0ba9dc09/TEXT","dcterms:extent":"0 KB"}],"edm:TimeSpan":{"@rdf:about":"1992-2025","edm:begin":{"@xml:lang":"en","#text":"1992"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-52I46PY6","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:SPR-WQVGMCSC"},{"@xml:lang":"sl","#text":"Acta dermatovenerologica Alpina, Pannonica et Adriatica"}],"dcterms:issued":"2025","dc:creator":"Kawen, Ahmed Abdulhussein","dc:format":[{"@xml:lang":"sl","#text":"letnik:34"},{"@xml:lang":"sl","#text":"številka:iss. 1"},{"@xml:lang":"sl","#text":"str. 7-12"}],"dc:identifier":["DOI:10.15570/actaapa.2025.5","ISSN:1318-4458","COBISSID_HOST:260113923","URN:URN:NBN:SI:doc-52I46PY6"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Slovene Welding Society"},"dc:subject":[{"@xml:lang":"en","#text":"androgenetic alopecia"},{"@xml:lang":"sl","#text":"androgenetska alopecija"},{"@xml:lang":"sl","#text":"angiogeneza lasnih mešičkov"},{"@xml:lang":"en","#text":"hair follicle angiogenesis"},{"@xml:lang":"en","#text":"hair regrowth"},{"@xml:lang":"en","#text":"oral minoxidil"},{"@xml:lang":"sl","#text":"peroralni minoksidil"},{"@xml:lang":"sl","#text":"ponovna rast las"},{"@xml:lang":"en","#text":"vascular endothelial growth factor"},{"@xml:lang":"sl","#text":"vaskularni endotelijski rastni faktor"}],"dcterms:temporal":{"@rdf:resource":"1992-2025"},"dc:title":{"@xml:lang":"sl","#text":"Effects of oral minoxidil on serum VEGF and hair regrowth in androgenetic alopecia|"},"dc:description":{"@xml:lang":"sl","#text":"Introduction: Androgenetic alopecia (AGA) is a common hair loss condition characterized by follicular miniaturization. Vascular endothelial growth factor (VEGF) plays a key role in promoting angiogenesis and supporting hair follicle growth. Oral minoxidil has been suggested to upregulate VEGF levels, enhancing hair regrowth. Methods: This prospective study included 50 participants divided into two groups: oral minoxidil (1 mg/day; n = 25) and control (n = 25). Serum VEGF levels were measured at baseline and after 12 weeks of treatment. Hair growth parameters, including hair count, diameter, shedding, and pull test results, were assessed systematically. Results: Baseline VEGF levels were similar between groups (p = 0.1873). Post-treatment, VEGF levels increased significantly in the minoxidil group (217.88 ± 22.65 pg/ml vs. 142.81 ± 23.14 pg/ml in the control, p < 0.0001). Hair count and diameter improved significantly (p < 0.0001 and p = 0.0040, respectively), with reductions in shedding and pull test results (p < 0.0001). Positive correlations were observed between VEGF and hair count (r = 0.9965), whereas shedding showed negative correlations (r = -0.5374). Conclusions: Oral minoxidil significantly enhances VEGF levels, promoting hair growth and reducing shedding. VEGF serves as a promising biomarker for assessing treatment effectiveness and understanding the angiogenic mechanisms involved in AGA"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-52I46PY6","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-52I46PY6"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-52I46PY6/43c2a934-5722-41a8-a654-f5c4df6bffe0/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Združenje slovenskih dermatovenerologov"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-52I46PY6/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-52I46PY6"}}}}