{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-4WNICUDI/a2a1025f-b22e-40c2-b1ac-edfbee3e64d6/PDF","dcterms:extent":"234 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-4WNICUDI/c1d0177a-07e0-4b59-8d70-910a93c47f14/TEXT","dcterms:extent":"28 KB"}],"edm:TimeSpan":{"@rdf:about":"2005-2025","edm:begin":{"@xml:lang":"en","#text":"2005"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-4WNICUDI","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-8ER5ZBJN"},{"@xml:lang":"sl","#text":"Farmacevtski vestnik"}],"dcterms:issued":"2021","dc:creator":["Proj, Matic","Toplak, Žan"],"dc:format":[{"@xml:lang":"sl","#text":"številka:1"},{"@xml:lang":"sl","#text":"letnik:72"},{"@xml:lang":"sl","#text":"str. 44-50"}],"dc:identifier":["ISSN:0014-8229","COBISSID_HOST:55511811","URN:URN:NBN:SI:doc-4WNICUDI"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"dc:subject":[{"@xml:lang":"sl","#text":"Podatkovne zbirke"},{"@xml:lang":"sl","#text":"računalniško podprto načrtovanje učinkovin"},{"@xml:lang":"sl","#text":"strojno učenje"},{"@xml:lang":"sl","#text":"Umetna inteligenca"},{"@xml:lang":"sl","#text":"Zdravila"}],"dcterms:temporal":{"@rdf:resource":"2005-2025"},"dc:title":{"@xml:lang":"sl","#text":"Uporaba umetne inteligence pri odkrivanju novih učinkovin| The use of artificial intelligence in drug discover|"},"dc:description":[{"@xml:lang":"sl","#text":"The rise of artificial intelligence in many fields is also making its way into the pharmaceutical industry and academic labs engaged in drug discovery. New algorithms for pattern recognition in ever-increasing amounts of data are already being used to support rational design. The scientific literature is replete with reports of applications in the areas of target discovery and structure preparation, virtual compound library design, discovery of new hit compounds and optimisation to lead compounds, preclinical and clinical trials. However, there are still a number of challenges that need to be addressed"},{"@xml:lang":"sl","#text":"Razmah umetne inteligence na številnih področjih prodira tudi v farmacevtsko industrijo in akademske laboratorije, ki se ukvarjajo z odkrivanjem novih učinkovin. Nove algoritme za iskanje vzorcev v vedno večjih količinah podatkov že uporabljamo za pomoč pri racionalnem načrtovanju učinkovin. V literaturi so opisali številne primere uporabe na področjih odkrivanja tarč in priprave njihove strukture, priprave virtualnih knjižnic spojin, načrtovanja novih spojin zadetkov, njihovo optimizacijo do spojin vodnic, predkliničnih in kliničnih raziskav. Kljub temu je na tem področju še veliko izzivov"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-4WNICUDI","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-4WNICUDI"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-4WNICUDI/a2a1025f-b22e-40c2-b1ac-edfbee3e64d6/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-4WNICUDI/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-4WNICUDI"}}}}