{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-40IH8NTP/bbcc7208-f419-4a5d-9f81-2400d5a46134/HTML","dcterms:extent":"27 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-40IH8NTP/5fe5f182-bde1-44ad-8780-19cd3a010b4d/PDF","dcterms:extent":"792 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-40IH8NTP/00b50d41-2666-4252-82fc-1c260f0f2b60/TEXT","dcterms:extent":"16 KB"}],"edm:TimeSpan":{"@rdf:about":"1992-2025","edm:begin":{"@xml:lang":"en","#text":"1992"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-40IH8NTP","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:SPR-WQVGMCSC"},{"@xml:lang":"sl","#text":"Acta dermatovenerologica Alpina, Pannonica et Adriatica"}],"dcterms:issued":"2011","dc:creator":["Fujs Komloš, Kristina","Jelen, Mateja","Kocjan, Boštjan","Košorok, Pavle","Poljak, Mario","Seme, Katja","Šterbenc, Anja"],"dc:format":[{"@xml:lang":"sl","#text":"letnik:20"},{"@xml:lang":"sl","#text":"številka:3"},{"@xml:lang":"sl","#text":"str. 155-160"}],"dc:identifier":["ISSN:1318-4458","COBISSID:29385433","URN:URN:NBN:SI:doc-40IH8NTP"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Slovene Welding Society"},"dc:subject":[{"@xml:lang":"en","#text":"Classification"},{"@xml:lang":"en","#text":"Eyebrows"},{"@xml:lang":"en","#text":"Genetics"},{"@xml:lang":"sl","#text":"Genotip"},{"@xml:lang":"sl","#text":"genotipizacija"},{"@xml:lang":"en","#text":"Genotype"},{"@xml:lang":"en","#text":"Hair Follicle"},{"@xml:lang":"sl","#text":"Lasni mešiček"},{"@xml:lang":"sl","#text":"Obrvi"},{"@xml:lang":"en","#text":"Papilloma"},{"@xml:lang":"en","#text":"Papillomavirus, Human"},{"@xml:lang":"en","#text":"Papilom"},{"@xml:lang":"sl","#text":"papiloma virusi"},{"@xml:lang":"sl","#text":"Papilomavirus človeški"},{"@xml:lang":"sl","#text":"Polimerazna, verižna reakcija"},{"@xml:lang":"en","#text":"Polymerase Chain Reaction"}],"dcterms:temporal":{"@rdf:resource":"1992-2025"},"dc:title":{"@xml:lang":"sl","#text":"Genomic distribution of beta papillomaviruses in single eyebrow hair samples and pools of eyebrow hair samples|"},"dc:description":{"@xml:lang":"sl","#text":"Human beta papillomaviruses (beta-HPVs) are frequently detected in hairs and the majority of people are infected with multiple beta-HPV genotypes. This study was conducted to investigate for the first time the distribution of beta-HPV genotypes in single hair specimens and to estimate the contribution of a single hair to the beta-HPV profile obtained from a specimen made of multiple hairs pooled together. A total of 85 eyebrow hair specimens, representing 64 single hairs and 21 pools of hairs, obtained from 21 immunocompetent individuals, were tested using a reverse-line blot-based beta-HPV genotyping assay that allows identification of 25 different beta-HPVs. Overall, beta-HPV DNA was detected in 82/84 (97.6%) samples. The great majority of hair pools (19/21; 90.5%) contained multiple beta-HPVs, the mean number of identified beta-HPV genotypes per hair pool was 5.2 (ranging from 1 to 12). In individual hairs, the great majority of individual hairs (43/63; 68.3%) contained multiple beta-HPVs, the mean number of identified beta-HPV genotypes was 4 (ranging from 1 to 12). Overall, HPV-23 was the most prevalent genotype, followed by HPV-24 and HPV-38. A comparison of beta-HPV genotype distribution in pooled hair specimens and in at least one individual hair within a single patient revealed that 5/20 patients had a complete match between the number and profile of identified genotypes, 2/20 patients had the same/similar number of HPV genotypes but different genotype profile, 9/20 patients had more HPV genotypes identified in pools than in the majority of individual hairs and 4/20 patients had at least one individual hair with more HPV genotypes identified than in the corresponding pool. Our results suggest that beta-HPVs are unevenly distributed over the eyebrows and even pools made of several hairs do not necessarily provide information on the whole spectrum of HPV genotypes present in eyebrows"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-40IH8NTP","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-40IH8NTP"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-40IH8NTP/5fe5f182-bde1-44ad-8780-19cd3a010b4d/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Združenje slovenskih dermatovenerologov"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-40IH8NTP/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-40IH8NTP"}}}}