25 KB108 KB22 KB199220252008Dastychová, EliškaNečas, MiroslavVašku, Vladimirletnik:17številka:2str. 61-68ISSN:1318-4458COBISSID:24540377URN:URN:NBN:SI:doc-3JJWPTDTenSlovene Welding SocietyActa dermatovenerologica Alpina, Pannonica et AdriaticaAntioksidantiantioxidantAntioxidantsdermatitisDermatitis kontaktniDermatitis, ContactdermatologijaEczemaEkcemExcipientsMazilne podlagepreventivaContact hypersensitivity to selected excipients of dermatological topical preparations anf cosmetics in patients with chronic eczema|Objective: 1) Assessment of the frequency of contact sensitization to selectedexcipients of dermatological topical preparations and cosmetics in patients with chronic eczema. 2) Detection of the sources of sensitization. Methods: 1,927 patients with chronic eczema (mean age 44.3 years, 601 males, 1,326 females) were patch tested with selected excipients. Results: The main rates of sensitization observed were: thiomersal 11.3%, wool alcohols 4.0%, phenylmercuric acetate 3.1%, formaldehyde 2.5%, dodecyl gallate 2.0%, Bronopol1.9%, dibromodicyanobutane/phenoxyethanol (1:4) 1.7%, chloracetamide 1.6%, chlorhexidine digluconate 1.5%, Kathon CG 1.4%, parabens 1.1%, diazolidinyl urea 0.9%, imidazolidinyl urea 0.7%, benzalkonium chloride 0.7%, and Quaternium-15 (quaternary ammonium salt) 0.7%. Conclusion: The rate of sensitization to the excipients included in dermatological topical preparations and cosmetics in patients with chronic eczema is significant. Complete information on all the ingredients is necessaryTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZdruženje slovenskih dermatovenerologov