{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-2OTY0FHI/893105da-ff55-4df6-ba6d-45d3cde7b5f0/PDF","dcterms:extent":"209 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-2OTY0FHI/cca53f95-0ff0-491a-8efa-2694c0b2648b/TEXT","dcterms:extent":"39 KB"}],"edm:TimeSpan":{"@rdf:about":"2005-2025","edm:begin":{"@xml:lang":"en","#text":"2005"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-2OTY0FHI","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-8ER5ZBJN"},{"@xml:lang":"sl","#text":"Farmacevtski vestnik"}],"dcterms:issued":"2015","dc:creator":["Janežič, Ana","Kos, Mitja"],"dc:format":[{"@xml:lang":"sl","#text":"številka:5"},{"@xml:lang":"sl","#text":"letnik:66"},{"@xml:lang":"sl","#text":"str. 378-386"}],"dc:identifier":["ISSN:0014-8229","COBISSID:4006257","URN:URN:NBN:SI:doc-2OTY0FHI"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"dc:subject":[{"@xml:lang":"sl","#text":"farmakoterapija"},{"@xml:lang":"sl","#text":"intervencije"},{"@xml:lang":"sl","#text":"pregled uporabe zdravil"},{"@xml:lang":"sl","#text":"sodelovanje"},{"@xml:lang":"sl","#text":"zdravljenje z zdravili"}],"dcterms:temporal":{"@rdf:resource":"2005-2025"},"dc:title":{"@xml:lang":"sl","#text":"Z dokazi podprte intervencije za izboljšanje sodelovanja pri zdravljenju z zdravili| Evidence-based interventions to improve medication adherence|"},"dc:description":[{"@xml:lang":"sl","#text":"Medication adherence represents a major challenge as generally only half of the patients with chronic diseases adhere to their treatment. The best adherence rates can be found in HIV patients who are treated with antiretrovirals, patients with rheumatoid arthritis, gastrointestinal diseases, cancer, epilepsy and neurological diseases, and the worst adherence rates in patients with sleep disorders, diabetes, respiratory diseases, and renal failure. Patient non-adherence is often a cause of the treatment failure, so effective interventions to optimize adherence are necessary. The research focuses on a range of possible interventions with regard to potential causes of non-adherence. Technical interventions for simplification of the dosing regimen, reminders, patient education and motivation also show promising results, but complex multifaceted interventions were shown to be the most effective. However, the success of interventions largely depends on the ability to identifiy non-adherence and its underlying causes as well as tayloring the interventions to individual patients' disease-related characteristics"},{"@xml:lang":"sl","#text":"Pri zdravljenju v največji meri sodelujejo pacienti, ki jih zdravimo z antiretrovirusnimi zdravili zaradi okužbe s HIV, pacienti z artritisom, boleznimi gastrointestinalnega trakta, rakavimi boleznimi, epilepsijo in nevrološkimi boleznimi, najmanj pa tisti z motnjami spanja, diabetesom, respiratornimi boleznimi in ledvično odpovedjo. Sodelovanje pacientov je tesno povezano z uspešnostjo terapije, zato so učinkovite intervencije za optimizacijo sodelovanja nujne. V raziskavah srečamo paleto možnih ukrepov, s katerimi glede na potencialne vzroke nesodelovanja k izzivu pristopamo na različne načine. Spodbudne rezultate kažejo predvsem tehnične intervencije z namenom poenostavitve režima odmerjanja zdravil ali opominjanja pacientov, svetovanje škatlic za zdravila ali priprava pretisnih omotov z dnevnimi odmerki zdravil v lekarni, izobraževanje ter motiviranje in spremljanje pacientov, kot najučinkovitejše pa raziskave kažejo kompleksne intervencije, ki združujejo več različnih strategij. Za uspešnost intervencij je kljub vsemu ključna ustrezna prepoznava nesodelovanja in vzrokov, ki se skrivajo v ozadju, ter prilagoditev intervencije individualnemu pacientu"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-2OTY0FHI","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-2OTY0FHI"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-2OTY0FHI/893105da-ff55-4df6-ba6d-45d3cde7b5f0/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-2OTY0FHI/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-2OTY0FHI"}}}}