26 KB119 KB25 KB200520252010Černelč, PeterDomanovič, DragoslavJazbec, JanezKrašna, Metkaštevilka:3letnik:61str. 139-143ISSN:0014-8229COBISSID:27432153URN:URN:NBN:SI:doc-2JKI917NslSlovensko farmacevtsko društvoFarmacevtski vestnikhematologijamatične celicepopkovnična kriSlovenska javna banka popkovnične krvi| Slovenian public cord blood bank|The public cord blood bank is a non-profit organization that processes and stores donated unrelated cord blood for haematopoietic stem cell transplantations. In the past year and half, 833 women donated cord blood to our bank, of which 267 units (32%) were stored. In the past three months, an average of 80 parents per month donated cord blood and 24 units per month werecryopreserved. The median number of leukocytes per cord blood unit prior cryopreservation was 977 x 106 (n = 125; 507 x 106 - 2631 x 106). The mean recovery of leukocytes after processing the cord blood with the Sepax cell separation system was 74% (n = 44; 38 - 94%). We are planning to start the accreditation process at the international registry EuroCord to achieve consistent production of high quality cord blood products that will comply with NetCord-FACT standardsJavna banka popkovnične krvi je nepridobitna organizacija, ki obdeluje in shranjuje darovano nesorodno popkovnično kri (PK), iz katere zagotavlja celične pripravke za zdravljenje nekaterih krvnih in metabolnih bolezni, pri katerih bolniki potrebujejo presaditev krvotvornih matičnih celic (KMC). V slovensko banko je v prvem letu in pol darovalo PK 833 žensk, glede na standardne kriterije pa smo shranili 267 (32%) enot PK. V zadnjih treh mesecihje PK darovalo približno 80 oseb na mesec, v povprečju pa smo od teh mesečno shranili 24 enot. Mediana števila levkocitov v pripravkih PK pred zamrzovanjem je bila 977 x 106 (n = 125; od 507 x 106 - 2631 x 106). Učinkovitost zbiranja levkocitov z aparatom Sepax pa je bila v povprečju 74% (n = 44; 38 - 94%). V bližnji prihodnosti nameravamo delovanje javne banke PK akreditirati pri mednarodnem registru EuroCord in s tem zagotoviti učinkovite pripravke, ki bodo dosegali standarde NetCord-FACTTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko farmacevtsko društvo