{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-25JXVA1X/d90f7a09-6842-4cea-b846-856c7ced200b/PDF","dcterms:extent":"2432 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-25JXVA1X/594e9799-60a0-45bf-88b2-96c28c99946d/TEXT","dcterms:extent":"11 KB"}],"edm:TimeSpan":{"@rdf:about":"1992-2025","edm:begin":{"@xml:lang":"en","#text":"1992"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-25JXVA1X","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:SPR-WQVGMCSC"},{"@xml:lang":"sl","#text":"Acta dermatovenerologica Alpina, Pannonica et Adriatica"}],"dcterms:issued":"1997","dc:creator":["Gwiezdzinski, Z...","Nierebinska, E...","Urbanowski, S..."],"dc:format":[{"@xml:lang":"sl","#text":"številka:2"},{"@xml:lang":"sl","#text":"letnik:6"},{"@xml:lang":"sl","#text":"str. 55-59"}],"dc:identifier":["ISSN:1318-4458","COBISSID_HOST:7338457","URN:URN:NBN:SI:doc-25JXVA1X"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Slovene Welding Society"},"dc:subject":[{"@xml:lang":"sl","#text":"Administration and dosage"},{"@xml:lang":"sl","#text":"Candidiasis, oral"},{"@xml:lang":"sl","#text":"Candidiasis, vulvovaginal"},{"@xml:lang":"sl","#text":"Drug therapy"},{"@xml:lang":"sl","#text":"Follow-up studies"},{"@xml:lang":"sl","#text":"Itraconazole"},{"@xml:lang":"sl","#text":"Therapeutic use"},{"@xml:lang":"sl","#text":"Treatment outcome"}],"dcterms:temporal":{"@rdf:resource":"1992-2025"},"dc:title":{"@xml:lang":"sl","#text":"Itraconazole in the therapy of candidosis of uro-genital system and/or oral cavity and throat mucosa in a daily dose of 100 mg|"},"dc:description":{"@xml:lang":"sl","#text":"The results of a clinical study on the effectiveness and tolerability of itraconazole used in oral therapy of candidosis in a single dose of 100 mg daily were presented. Investigations were performed in 3 groups: 20 persons with candidosis of the urogenital system, 18 persons with candidosis of the oral cavity and throat mucosa. All strains of yeast-like fungi isolated from patients were susceptible to itraconazole. The values of MIC were from 0,01 to20,0 ug/ml. In three groups of patients results and duration of treatment were: 1st group - 90%, from 4 to 8 days; 2nd group - 88,9%, from 4 days to 10 weeks; 3rd group - 90%, from 4 days to 12 weeks. Two weeks after the end of the therapy the recurrence of the disease was observed in 4 persons (8,3%). In2 patients (4,2%), transient adverse reactions - neusea and stomach ache were observed. No changes in laboratory tests (Aspat, Alat, bilirubin) were noticed. It was concluded that itraconazole applied in a single dose of 100 mgdaily is effective and safe. In the authors' opinion therapy should be continued until negative results of clinical and mycological studies of all morbid yeast foci"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-25JXVA1X","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-25JXVA1X"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-25JXVA1X/d90f7a09-6842-4cea-b846-856c7ced200b/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Združenje slovenskih dermatovenerologov"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-25JXVA1X/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-25JXVA1X"}}}}