{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-15YS6IFG/b8116035-09c2-46d1-8349-f82629235c26/PDF","dcterms:extent":"219 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:doc-15YS6IFG/9191701f-4c75-4b4f-9c7a-a27eae071bd6/TEXT","dcterms:extent":"17 KB"}],"edm:TimeSpan":{"@rdf:about":"2005-2025","edm:begin":{"@xml:lang":"en","#text":"2005"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:doc-15YS6IFG","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-8ER5ZBJN"},{"@xml:lang":"sl","#text":"Farmacevtski vestnik"}],"dcterms:issued":"2025","dc:creator":"Škrgat, Sabina","dc:format":[{"@xml:lang":"sl","#text":"številka:2"},{"@xml:lang":"sl","#text":"letnik:76"},{"@xml:lang":"sl","#text":"str. 74-77"}],"dc:identifier":["ISSN:0014-8229","COBISSID_HOST:271036419","URN:URN:NBN:SI:doc-15YS6IFG"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"dc:subject":[{"@xml:lang":"en","#text":"airway damage"},{"@xml:lang":"sl","#text":"Astma"},{"@xml:lang":"sl","#text":"Dihala"},{"@xml:lang":"sl","#text":"Dušikov oksid"},{"@xml:lang":"sl","#text":"Eozinofilija"},{"@xml:lang":"en","#text":"exhaled air"},{"@xml:lang":"sl","#text":"izdihani zrak"},{"@xml:lang":"sl","#text":"okvara dihalne poti"}],"dcterms:temporal":{"@rdf:resource":"2005-2025"},"dc:title":{"@xml:lang":"sl","#text":"Endotipi astme, povezani z nepovratno okvaro dihalne poti| Asthma endotypes linked with airway damage|"},"dc:description":[{"@xml:lang":"sl","#text":"Asthma is heterogeneus disease. Airway inflammation that persists leads to an irreversible loss of pulmonary function. Asthma with pronounced eosinophilia in the blood and increased concentration of nitric oxide in exhaled air is associated with an uncontrolled clinical pattern, impaired lung function and frequent exacerbations. The purpose of this paper is to present the modern approach toward a patient with asthma. This includes the basics of recognizing persistent inflammation in the asthma airway, which otherwise poses a risk of frequent exacerbations of the disease and airway damage"},{"@xml:lang":"sl","#text":"Astma je po svojem kliničnem poteku heterogena bolezen. Vnetje, ki na ravni dihalne poti vztraja, vodi v nepovratno izgubo pljučne funkcije. Astma z izraženo eozinofiijo v krvi in povišano koncentracijo dušikovega oksida v izdihanem zraku je povezana z nekontrolirano klinično sliko, slabšo pljučno funkcijo in pogostimi poslabšanji bolezni, zato je te bolnike potrebno pravočasno prepoznati in zdraviti. Namen prispevka je predstavitev sodobnega pristopanja k bolniku z astmo. Ta vključuje temelje prepoznavanja perzistentnega vnetja na ravni dihalne poti, ki sicer predstavlja tveganje za pogosta poslabšanja bolezni in okvaro dihalne poti pri bolniku z astmo"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:doc-15YS6IFG","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:doc-15YS6IFG"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:doc-15YS6IFG/b8116035-09c2-46d1-8349-f82629235c26/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko farmacevtsko društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:doc-15YS6IFG/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:doc-15YS6IFG"}}}}