203 KB12 KB199220251999Barsnick, PeterBeeke, ErikWagner, Wolfgangštevilka:1letnik:33str. 55-58ISSN:1318-2099COBISSID_HOST:9752793URN:URN:NBN:SI:doc-ZUZ5YZ9EenCroatian Medical Association - Croatian Society of RadiologySlovenian Medical Society - Section of RadiologyRadiology and oncology (Ljubljana)Age factorsChoroidMuscular atrophyNeovascularization, pathologicRadiotherapyVisual acuityRadiotherapy for choroidal neovascularisation of age-related macular degeneration| Radioterapija neovaskularizirane žilnice pri starostni makularni degeneraciji|Age-related macular degeneration caused by choroidal neovascularisation is an increasing problem in ophthalmology. The results of the therapy in the past were poor or associated with a numher of side, effects. Recently, some reportshave shown a beneficial effect of low-dose irradiation. Therefore, we reviewed the data of our patients included in a pilot study to confirm the very preliminary data in literature. Fourtythree patients were irradiated witha linear accelerator (6 MV ) at a total dose of 16 Gy. Six months after irradiation, 69% of our patients maintained or improved their visual acuity. We did not observe side effects or any acute or late sequelae within a median follow-up period of 12 monthsStarostna makularna degeneracija zaradi neovaskularizacije žilnice predstavljav oftalmologiji vse večji problem. Zdravljenje doslej ni bilo preveč uspešno in obenem povezano s številnimi stranskimi učinki. Pred kratkimpa smo zasledili ugodne rezultate zdravljenja z obsevanje z nizkimi dozami. Zato smo ponovno proučili podatke o bolnikih, vključenih v pilotsko študijo, da bi lahko potrdili v literaturi objavljene podatke. Raziskava je zajemala 43 bolnikov, ki smo jih obsevali z lineranim akceleratorjem (6 MV) pri skupni dozi l6Gy. Šest mesecev po zaključenem zdravljenju se je pri 69% bolnikov ostrina vida ohranila ali celo izboljšala. Pri proučevanju stran- skih učinkov pa v času spremljanja bolezni v povprečju 12 mesecev nismo zasledili niti akutnih niti kasnih posledic zdravljenjaTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaOnkološki inštitut Ljubljana