{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-ZQXMAN0X/40b15b1d-f61f-4b28-a8c5-9c5d16e2d425/PDF","dcterms:extent":"243 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-ZQXMAN0X/63453f7a-5d38-45c6-a795-0b376364d82a/TEXT","dcterms:extent":"45 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:DOC-ZQXMAN0X","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2023","dc:creator":["Bizjak, Bojana","Bricl, Irena","Lehner, Natalija"],"dc:contributor":"Lehner, Natalija","dc:format":[{"@xml:lang":"sl","#text":"1-9 str."},{"@xml:lang":"sl","#text":"letnik:92"},{"@xml:lang":"sl","#text":"številka:iss. 1-2  prispevka 3336"}],"dc:identifier":["DOI:10.6016/ZdravVestn.3336","COBISSID_HOST:140641539","ISSN:1581-0224","URN:URN:NBN:SI:doc-ZQXMAN0X"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"en","#text":"immunoglobuline anti-D"},{"@xml:lang":"sl","#text":"imunoglobulin anti-D"},{"@xml:lang":"en","#text":"predicted fetal phenotype RhD"},{"@xml:lang":"sl","#text":"predviden plodov fenotip RhD"},{"@xml:lang":"sl","#text":"presejalni test"},{"@xml:lang":"en","#text":"preventive inoculation"},{"@xml:lang":"sl","#text":"preventivno injiciranje"},{"@xml:lang":"en","#text":"screening test"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"Ciljana zaščita RhD-negativnih nosečnic z imunoglobulinom anti-D v 28. tednu nosečnosti v severovzhodni Sloveniji| Targeted prophylaxis in RhD-negative pregnant women with anti-D immunoglobulin in the 28th week of pregnancy in northeastern Slovenia|"},"dc:description":[{"@xml:lang":"sl","#text":"Targeted protection is a program that allows noninvasive determination of the fetal RHD genotype from the peripheral blood of an RhD-negative pregnant woman based on a screening test. Prior to the introduction of predicted RhD pheno-typing, all RhD-negative pregnant women received protection with anti-D immunoglobulin at 28 to 30 weeks of pregnancy. In Europe, 40% of RhD-negative pregnant women carry an RhD negative foetus and do not develop D antigen sensitization. With the introduction of mentioned test pregnant women receive immunoglobulin anti-D targeted protection according to the predicted foetal RhD phenotype. With the introduction of the national programme Slovenia has become one of the few countries worldwide implementing targeted protection with anti-D immunoglobulin"},{"@xml:lang":"sl","#text":"Ciljana zaščita z imunoglobulinom anti-D je program, ki na podlagi presejalnega testa omogoča neinvazivno določitev plodovega genotipa RHD iz periferne krvi RhD-negativne nosečnice. Pred uvedbo določanja predvidenega fenotipa RhD so vse RhD-negativne nosečnice prejele zaščito z imunoglobulinom anti-D v 28.–30. tednu nosečnosti. V Evropi 40 % RhD-negativnih nosečnic nosi RhD-negativen plod in zaščite ne potrebuje, saj med materjo in plodom ni RhD-neskladnosti in zato ni nevarnosti senzibilizacije na antigen RhD. Z uvedbo tega testa pa nosečnice zaščito z imunoglobulinom anti-D prejmejo ciljano glede na predvideni plodov fenotip RhD. Z uvedbo nacionalnega programa je Slovenija postala ena redkih držav v svetovnem merilu, ki izvaja ciljano zaščito z imunoglobulinom anti-D"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:DOC-ZQXMAN0X","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:DOC-ZQXMAN0X"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:DOC-ZQXMAN0X/40b15b1d-f61f-4b28-a8c5-9c5d16e2d425/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:DOC-ZQXMAN0X/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:DOC-ZQXMAN0X"}}}}