{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-Y541Y3AJ/98c45997-177b-4612-9834-1e85472fff04/HTML","dcterms:extent":"141 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-Y541Y3AJ/f2d0df76-7e7b-42ad-ba02-4181ec5d6339/PDF","dcterms:extent":"1006 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-Y541Y3AJ/0fca539d-5bba-4bc4-8cae-a011c5bf2b60/TEXT","dcterms:extent":"61 KB"}],"edm:TimeSpan":{"@rdf:about":"2000-2024","edm:begin":{"@xml:lang":"en","#text":"2000"},"edm:end":{"@xml:lang":"en","#text":"2024"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:DOC-Y541Y3AJ","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-fzwbu7gu"},{"@xml:lang":"sl","#text":"Image analysis and stereology"}],"dcterms:issued":"2008","dc:creator":"Angulo, Jesús","dc:format":[{"@xml:lang":"sl","#text":"18 strani"},{"@xml:lang":"sl","#text":"številka:2"},{"@xml:lang":"sl","#text":"letnik:27"},{"@xml:lang":"sl","#text":"str. 107-124"}],"dc:identifier":["ISSN:1580-3139","COBISSID:24560601","URN:URN:NBN:SI:doc-Y541Y3AJ"],"dc:language":"en","dc:publisher":{"@xml:lang":"sl","#text":"Društvo za stereologijo in kvantitativno analizo slike, Medicinska fakulteta"},"dc:subject":[{"@xml:lang":"sl","#text":"genom"},{"@xml:lang":"en","#text":"Image Processing, Computer-Assisted"},{"@xml:lang":"sl","#text":"matematična morfologija"},{"@xml:lang":"en","#text":"Oligonucleotide Probes"},{"@xml:lang":"sl","#text":"Oligonukleotidne sonde"},{"@xml:lang":"sl","#text":"Slika, obdelava z računalnikom"},{"@rdf:resource":"http://www.wikidata.org/entity/Q7020"}],"dcterms:temporal":{"@rdf:resource":"2000-2024"},"dc:title":{"@xml:lang":"sl","#text":"Polar modelling and segmentation of genomic microarray spots using mathematical morphology|"},"dc:description":{"@xml:lang":"sl","#text":"Robust image analysis of spots in microarrays (quality control + spot segmentation + quantification) is a requirement for automated software which is of fundamental importance for a high-throughput analysis of genomics microarray-based data. This paper deals with the development of model-based image processing algorithms for qualifying/segmenting/quantifying adaptively each spot according to its morphology. A series of morphologicalmodels for spot intensities are introduced. The spot typologies representmost of the possible qualitative cases identified from a large database (different routines, techniques, etc.). Then, based on these spot models, a classification framework has been developed. The spot feature extraction and classification (without segmenting) is based on converting the spot image to polar coordinates and, after computing the radial/angular projections, the calculation of granulometric curves and derived parameters from these projections. Spot contour segmentation can also be solved by working in polar coordinates, calculating the up/downminimal path, which is easily obtained with the generalized distance function. With this model-based technique, the segmentation can be regularised by controlling different elements of the algorithm. According to the spot typology (e.g., doughnut-like or egg-like spots), several minimal paths can be computed to obtain a multi-region segmentation. Moreover, this segmentation is more robust and sensible to weak spots, improving the previous approaches"},"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:DOC-Y541Y3AJ","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:DOC-Y541Y3AJ"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:DOC-Y541Y3AJ/f2d0df76-7e7b-42ad-ba02-4181ec5d6339/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Društvo za stereologijo in kvantitativno analizo slike"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:DOC-Y541Y3AJ/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:DOC-Y541Y3AJ"}}}}