26 KB537 KB25 KB192920262011Bevc, Sebastjanštevilka:11letnik:80str. 838-844ISSN:1318-0347COBISSID:29141721URN:URN:NBN:SI:doc-TSHQ5QQEslSlovensko zdravniško društvoZdravniški vestnikAldosteronAldosteroneAngiotensin-Converting Enzyme InhibitorsAngiotenzin-pretvorba, encimski inhibitorjiAntagonists And InhibitorsdrugKidney Failurekronična ledvična bolezenLedvična odpovedReceptorji aldosteronskiReceptors, AldosteronetherapyzdravilazdravljenjeAldosteron, zaviralci aldosteronskih receptorjev in kronična ledvična bolezen| Aldosterone, aldosterone receptor blockers and chronic kidney disease|Chronic kidney disease (CKD) is a worldwide public health problem and an important risk factor for cardiovascular events, morbidity and mortality. The renin-angiotensin-aldosteron system (RAAS) drugs, angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers contribute to a better evaluation of patients with CKD. Despite good efficacy of mentioned drugs, progressive decline of kidney function was observed, suggesting a hypothesis that both aldosterone activity related mechanism and some RAAS independent mechanisms may result in progressive kidney failure. The author of the articledescribed the role of aldosterone and aldosterone receptor blockers in patients with CKDTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo