{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-T68DCS4W/995fd61d-0bf2-4b0a-8bb4-c3b266bafba6/PDF","dcterms:extent":"659 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-T68DCS4W/593b0508-128a-4322-b001-8c271ed95e30/TEXT","dcterms:extent":"28 KB"}],"edm:TimeSpan":{"@rdf:about":"2022-2025","edm:begin":{"@xml:lang":"en","#text":"2022"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:DOC-T68DCS4W","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-UCB4A42Q"},{"@xml:lang":"sl","#text":"Placebo"}],"dcterms:issued":"2025","dc:creator":"Razpotnik, Saša","dc:format":[{"@xml:lang":"sl","#text":"številka:4"},{"@xml:lang":"sl","#text":"str. 32-36"}],"dc:identifier":["COBISSID_HOST:248500483","ISSN:2820-5014","URN:URN:NBN:SI:doc-T68DCS4W"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Fakulteta za farmacijo, ŠSSFD"},"dc:subject":[{"@xml:lang":"en","#text":"antibiotic treatment"},{"@xml:lang":"en","#text":"chlamydia"},{"@xml:lang":"sl","#text":"gonoreja"},{"@xml:lang":"en","#text":"gonorrhoea"},{"@xml:lang":"sl","#text":"klamidijska okužba"},{"@xml:lang":"sl","#text":"nove terapije"},{"@xml:lang":"en","#text":"novel therapies"},{"@xml:lang":"en","#text":"pathophysiology of sexually transmitted bacterial infections"},{"@xml:lang":"sl","#text":"patofiziologija spolno prenosljivih bakterijskih okužb"},{"@xml:lang":"en","#text":"sexually transmitted bacterial infections"},{"@xml:lang":"sl","#text":"sifilis"},{"@xml:lang":"sl","#text":"Spolne bolezni"},{"@xml:lang":"sl","#text":"spolno prenosljive bakterijske bolezni"},{"@xml:lang":"en","#text":"syphilis"},{"@xml:lang":"sl","#text":"Zdravljenje"},{"@xml:lang":"sl","#text":"zdravljenje z antibiotiki"}],"dcterms:temporal":{"@rdf:resource":"2022-2025"},"dc:title":{"@xml:lang":"sl","#text":"Pregled bakterijskih spolno prenosljivih bolezni (gonoreja, sifilis, klamidijska okužba)| splošno o dermatoveneroloških boleznih|"},"dc:description":[{"@xml:lang":"sl","#text":"Syphilis, gonorrhoea, and chlamydia are key representatives of bacterial sexually transmitted diseases and the treatment of such diseases is becoming more and more challenging due to the emergence of antimicrobial resistance to established therapies. The consequences of inefficient treatment can be extremely debilitating to the affected (the development of neurosyphilis, cardiosyphilis, dementia, infertility, ectopical pregnancy), and can be harmful to congenitally infected infants (underdeveloped immune system, greater risk of complications, blindness due to conjunctival infection). Due to the potentially severe nature of the infections it is crucial that we establish a good understanding of their pathophysiology, which can enable further research, discovery and development of effective and innovative therapies, that exceed the established antibiotic treatments"},{"@xml:lang":"sl","#text":"Sifilis, gonoreja in klamidijska okužba spadajo med bakterijske spolno prenosljive bolezni, ki zaradi možnosti razvoja večkratne odpornosti proti antibiotikom predstavljajo vedno večji izziv za svetovno zdravstvo. Posledice neustreznega zdravljenja so lahko za pacienta izjemno škodljive (razvoj nevrosifilisa, kardiosifilisa, demence, neplodnosti, ektopičnih zanositev), prav tako lahko vodijo v ogroženost kongenitalno okuženih novorojenčkov (manj razvit imunski sistem, večja možnost komplikacij, slepota zaradi konjunktivalnih okužb). Zaradi resnosti okužb in njihovih zapletov je pomembno, da razumemo patofiziološke mehanizme njihovega razvoja, kar nam lahko omogoča odkritje in razvoj novih učinkovitih in inovativnih terapij, ki presegajo ustaljeno zdravljenje z antibiotiki"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:DOC-T68DCS4W","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:DOC-T68DCS4W"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:DOC-T68DCS4W/995fd61d-0bf2-4b0a-8bb4-c3b266bafba6/PDF"},"edm:rights":{"@rdf:resource":"http://rightsstatements.org/vocab/InC/1.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:dataProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:DOC-T68DCS4W/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:DOC-T68DCS4W"}}}}