41 KB755 KB30 KB200020242011Oorschot, Dorothy Eveštevilka:1letnik:30str. 1-9ISSN:1580-3139COBISSID:28383961URN:URN:NBN:SI:doc-T5UYTLPWenDruštvo za stereologijo in kvantitativno analizo slike, Medicinska fakultetaImage analysis and stereologyAnimals, NewbornAnoksijaAnoxiaCelica, preživetjeCell SurvivalCerebral IschemiaImage Processing, Computer-AssistedInjuriesmožganiNeuronsNevroniOrgan WeightOrgan, težapodganePodgane, Sprague-DawleyRats, Sprague-DawleySlika, obdelava z računalnikomstereologijaŽivali novorojeneIndirect measures of neuroprotection are parameters to avoid| examples from research on neonatal rat hypoxia-ischemia|The use of indirect measures of neuronal injury or neuroprotection, such as brain weight or the neuronal density of neurons, can lead to misinterpretations of biological processes. The use of modern stereological methods to directly measure the absolute number of surviving neurons generallyyields more reliable conclusions. The aim of this review is to provide some worked examples of this principle. The worked examples are obtained from research completed over the past 13 years on the investigation of potential neuroprotective therapies for moderate brain injury after neonatal hypoxia-ischemia in the ratTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaDruštvo za stereologijo in kvantitativno analizo slike