27 KB103 KB23 KB192920262002Kornhauser-Cerar, LilijanaStirn-Kranjc, Brankaletnik:71str. II-105-II-108številka:supl. 2ISSN:1318-0347COBISSID:14714329URN:URN:NBN:SI:doc-RWZGNPRXslSlovensko zdravniško društvoZdravniški vestnikbabyDiagnosisDojenčekGestacijska starostGestational ageInfantInfant, prematuremotnjeNedonošenčeknedonošenčkioftalmologijaRetinopathy of prematurityRetinopatija pri nedonošenčkihRetrospective studiesRetrospektivne študijevidVid, motnjeVid, ostrinaVision disordersVisual acuityVid nedonošenčkov| analiza nedonošenčkov, rojenih v ljubljanski porodnišnici 1990-1999| analysis of preterm infants born in Ljubljana 1990-1999| Visual outcome in preterm infants|Background. Improved perinatal care has increased the survival rate of prematurely born infants. An epidemiological fact that 6-18% and more visuallyimpaired children were prematurely born, emphasises the effect of premature birth on both visual function and development. Despite better knowledge on retinopathy of prematurity (ROP) it is stressed not to underestimate refractive errors, strabismus and visual impairment after brain lesions, being more common in preterm babies. Methods. Over 1300 preterm infants with a birth weight of 1500g or less and gestational age of 30 weeks or less, born in Maternity Hospital of Ljubljana, Slovenia in the period 1990-1999 were examined according to contemporary paediatric ophthalmologic recommendations. At least one year ophthalmologic follow-up (average 3.5 years) of 594 prematurely born infants with high neonatal risk factors for ROPand with general health problems, was performed. Sex, gestational age, birth weight, artificial ventilation, exchange blood transfusion, bronchopulmonary dysplasia, respiratory distress syndrome, apnoea, septicaemia, intraventricular haemorrhage, hyperbilirubinemia were analysed for correlation with ROP and visual impairment. Results. The survival rate of the studied preterm infants was 65-87% (mean 77.3%). ROP stage 1, 2 has developed in 33 children with a birth weight under 900g and in 10 with a birthweight 900-1200 g (altogether in 8%). ROP stage 3-5 has been registered (with or without plus disease) in 7 children (below 6%). In 6 children cryo orargon laser photocoagulation has been performed and vitreoretinal surgery in1 child (without functional results). In the studied group altogether 4 children (below 1%) became blind (visual acuity <0.05), all of them have had septicaemia. (Abstract truncated at 2000 characters)Izhodišča. Boljša obporodna oskrba je povečala preživetje tudi zelo nezrelih nedonošenčkov. Kjub temu je nedonošenost še povezana s slabovidnostjo ali slepoto z 10 do 18-odstotnim deležem med slepimi in slabovidnimi. Za oceno izida vidne funkcije nedonošenčkov, rojenih v ljubljanski porodnišnici, smo naredili analizo za nedonošenčke, rojene v obdobju 1990-1999. Metode. Podan jeoftalmološki pogled na nedonošenost in z njo povezane težave. Napravljena jeretrospektivna študija na podlagi podatkov Kliničnega oddelka za perinatologijo ljubljanske porodnišnice in oftalmoloških pregledov pri odkrivanju retinopatije nedonošenčka (ROP), njenem zdravljenju in sledenju razvoja vida. V zadnjih desetih letih smo pregledali preko 1300 nedonošenčkov,analiza pa zajema 594 nedonošenčkov, rojenih s porodno težo =< 1500 g in gestacijsko starostjo s =< 30 tednov, ki smo jih oftalmološko spremljali vsaj eno leto, povprečno pa 3 leta in pol. Povezavo z ROP oziroma vidno okvaro smo iskali glede na spol, gestacijsko starost, porodno težo, umetno ventilacijo, izmenjalno krvno transfuzijo, kronično pljučno bolezen, hialinsko-membransko bolezen pljuč, sepso, intraventrikularno krvavitev, hiperbilirubinemijo. Rezultati. Preživetje živorojenih novorojencev s porodno težo =< 1500 g in gestacijsko starostjo =< 30 tednov za ljubljansko porodnišnico v obdobju 1990-1999 je bilo 65-87% (povprečno 77,3%). ROP, stadij1,2 smo ugotovili pri 33 otrocih s porodno težo pod 900 g in pri 10 s porodno težo 900-1200 g (skupaj v 8%). ROP, stadij 3-5 (z ali brez "plus disease") je imelo 7 otrok (pod 6%). Mrežnico smo kriokoagulirali ali fotokoagulirali (argon laser) pri 6 otrocih, pri 1 je bil napravljen vitreoretinalni poseg (funkcionalno neuspešen). V analizirani skupini so oslepeli (vidna ostrina < 0.05) 4 otroci (pod 1%), vsi so preboleli sepso. (Izvleček skrajšan pri 2000 znakih)TEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo