252 KB23 KB202220252022Breznik, NikaPotisk, Katjaštevilka:1str. 4-7COBISSID_HOST:122806019ISSN:2820-5014URN:URN:NBN:SI:doc-QY1I5UU0enslFakulteta za farmacijo, ŠSSFDPlaceboinflammatory bowel diseaseKronična vnetna črevesna bolezenulcerative colitisUlcerozni kolitisUlcerozni kolitis|Chronic inflammatory bowel disease is a group of inflammatory bowel diseases, including Crohn's disease, ulcerative colitis, and intermediate colitis. The most frequent form of inflammatory bowel disease is ulcerative colitis. Its incidence is higher in the developed world and is still growing. Ulcerative colitis is a gastrointestinal disease of unknown etiology, usually lasting a lifetime. It is characterized by a chronic course with frequent flares and intermediate periods of variable length of remission. Symptoms of ulcerative colitis are diverse. The most common are abdominal pain and blood in the stool. Some patients may experience extra-intestinal manifestations of the disease. Diagnosis of ulcerative colitis begins with an analysis of the patient's history and a clinical examination and is confirmed via the laboratory, radiological, endoscopic, and histological examinations. The purpose of treatment is to achieve remission and prevent disease onset. Healing is only possible with a complete colectomyKronične vnetne črevesne bolezni so skupina dolgotrajnih (kroničnih) vnetnih obolenj črevesa. Mednje spadajo Crohnova bolezen, ulcerozni kolitis in intermediarni kolitis. Najpogostejša oblika vnetne črevesne bolezni je ulcerozni kolitis, ki se pojavlja med 15. in 30. letom starosti, predvsem v razvitih državah, kjer njegova incidenca narašča. Ulcerozni kolitis je bolezen neznane etiologije, ki navadno traja vse življenje. Bolezen poteka v obliki zagonov in remisij, klinična slika bolnikov z ulceroznim kolitisom pa je lahko precej različna. Najpogosteje se pojavljata bolečina v abdominalnem predelu in kri v blatu. Pri deležu bolnikov lahko pride do zunajčrevesnih manifestacij bolezni. Diagnostika ulceroznega kolitisa se začne s kliničnim pregledom in anamnezo, bolezen pa potrdimo z laboratorijskimi, radiološkimi, endoskopskimi in histološkimi preiskavami, pri čemer sta najpomembnejši zadnji dve. Z zdravljenjem želimo doseči remisijo in preprečiti zagone bolezni. Ozdravitev je možna le s popolno kolektomijoTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of Slovenia