{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-PBADBNHM/c15ce068-4d9d-4555-9dbd-8c0d8e8663bb/HTML","dcterms:extent":"41 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-PBADBNHM/ccdc14f1-226c-4d89-bff1-cf2a1a14f9e1/PDF","dcterms:extent":"144 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-PBADBNHM/06488570-7160-497b-b8e6-c706aec87d7c/TEXT","dcterms:extent":"32 KB"}],"edm:TimeSpan":{"@rdf:about":"1998-2025","edm:begin":{"@xml:lang":"en","#text":"1998"},"edm:end":{"@xml:lang":"en","#text":"2025"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:DOC-PBADBNHM","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/URN:NBN:SI:spr-KC6O72BG"},{"@xml:lang":"sl","#text":"Acta chimica slovenica"}],"dcterms:issued":"2011","dc:creator":"Bavec, Aljoša","dc:format":[{"@xml:lang":"sl","#text":"številka:2"},{"@xml:lang":"sl","#text":"letnik:58"},{"@xml:lang":"sl","#text":"str. 195-202"}],"dc:identifier":["ISSN:1318-0207","COBISSID:28681689","URN:URN:NBN:SI:doc-PBADBNHM"],"dc:language":"en","dc:publisher":[{"@xml:lang":"sl","#text":"Slovenian Chemical Society"},{"@xml:lang":"sl","#text":"Slovensko kemijsko društvo"}],"dc:subject":[{"@xml:lang":"en","#text":"Arachidonic Acid"},{"@xml:lang":"sl","#text":"Arahidonska kislina"},{"@xml:lang":"sl","#text":"Citosol"},{"@xml:lang":"en","#text":"Cytosol"},{"@xml:lang":"en","#text":"Eicosanoids"},{"@xml:lang":"sl","#text":"Eikozanoidi"},{"@xml:lang":"sl","#text":"encimi"},{"@xml:lang":"sl","#text":"Fosfolipaze A"},{"@xml:lang":"sl","#text":"Fosfolipidi"},{"@xml:lang":"sl","#text":"Lizofosfolipidi"},{"@xml:lang":"en","#text":"Lysophospholipids"},{"@xml:lang":"en","#text":"Metabolism"},{"@xml:lang":"en","#text":"Pharmacology"},{"@xml:lang":"en","#text":"Phospholipases A"},{"@xml:lang":"en","#text":"Phospholipids"}],"dcterms:temporal":{"@rdf:resource":"1998-2025"},"dc:title":{"@xml:lang":"sl","#text":"Structure, function and regulation of group IV phospholipase A2 family|"},"dc:description":[{"@xml:lang":"sl","#text":"The Group IV phospholipase A2 family is consisted of six intracellular enzymes. They catalyze hydrolysis of the sn-2 ester bond of glycerophospholipids, releasing fatty acid metabolites and lysophospholipids. Agonist-induced release of arachidonic acid for the production of eicosanoids by PLA2IValpha enzyme is important in regulating normal and pathological processes in a variety of target tissues. Here, we compare PLA2IValpha, and its paralogs beta, gamma, delta, epsilon and zeta in term of of their structure, function and regulation"},{"@xml:lang":"sl","#text":"Skupina IV fosfolipaz A2 trenutno obsega šest encimov. Encimi katalizirajo hidrolizo sn-2 estrske vezi glicerofosfolpidov, pri čemer nastane maščobna kislina in lizofosfolipid. Največkrat je produkt hidrolize arahidonska kislina, ki se pretvarja v aktivne eikozanoide, ki imajo pomembno vlogo pri regulaciji celičnih procesov v različnih tarčnih tkivih. V tem prispevku si bomo pogledali strukturo, funkcijo in regulacijo encima PLA2IValpha in jo primerjali z ostalimi predstavniki skupine IV fosfolipaz A2, in sicer z beta, gama, delta, epsilon in zeta"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:DOC-PBADBNHM","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:DOC-PBADBNHM"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:DOC-PBADBNHM/ccdc14f1-226c-4d89-bff1-cf2a1a14f9e1/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko kemijsko društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:DOC-PBADBNHM/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:DOC-PBADBNHM"}}}}