{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-P7FENLI0/572bdb84-7b28-44d0-9c47-ffc55b1fd39c/HTML","dcterms:extent":"22 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-P7FENLI0/7d96f228-9ce8-4dab-a9c5-1af9702489a0/PDF","dcterms:extent":"87 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-P7FENLI0/65602b7d-fd35-4d11-9b89-6f1fd8fa0c98/TEXT","dcterms:extent":"21 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:DOC-P7FENLI0","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2006","dc:creator":["Kasnik, Darja","Uranjek, Jasna"],"dc:format":[{"@xml:lang":"sl","#text":"številka:12"},{"@xml:lang":"sl","#text":"5 strani"},{"@xml:lang":"sl","#text":"letnik:75"},{"@xml:lang":"sl","#text":"str. 833-837"}],"dc:identifier":["ISSN:1318-0347","COBISSID:22408921","URN:URN:NBN:SI:doc-P7FENLI0"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"sl","#text":"Adneksitis"},{"@xml:lang":"en","#text":"Adnexitis"},{"@xml:lang":"en","#text":"Adult"},{"@xml:lang":"en","#text":"Adverse Effects"},{"@xml:lang":"en","#text":"Candida"},{"@xml:lang":"sl","#text":"Candida krusei"},{"@xml:lang":"sl","#text":"infekcijske bolezni"},{"@xml:lang":"en","#text":"Intrauterine Devices"},{"@xml:lang":"sl","#text":"Intrauterini vložki"},{"@xml:lang":"sl","#text":"Kandida"},{"@xml:lang":"sl","#text":"Odrasli"},{"@xml:lang":"sl","#text":"pelvično vnetje"},{"@xml:lang":"sl","#text":"Pljučnica"},{"@xml:lang":"en","#text":"Pneumonia"},{"@xml:lang":"en","#text":"therapy"},{"@xml:lang":"sl","#text":"zdravljenje"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"Pljučnica, povzročena s Candido krusei, kot zaplet zdravljenja tubo-ovarijskega abscesa| Candida krusei pneumonia as a complication of a tuboovarian abscess treatment| case report| prikaz primera|"},"dc:description":[{"@xml:lang":"sl","#text":"Background Frequency of infections, caused by Candida glabrata and Candida krusei, which are more resistant to fluconazole, is increasing among hospitalised patients, especially among patients in intensive care units (ICU). Systemic Candida infections are particularly dangerous. Pneumonia, caused by Candida species, most commonly albicans, rarely others, is a seriousinfection especially for immunocompromised patients. It's often fatal. We present a case report of a serious lung infection with fluconazole resistant Candida krusei in a 42 year-old previously healthy patient with perforated tuboovarian abscess (TOA), consecutive severe sepsis and septic shock. Patient used intrauterine device (IUD) for 17 years without any gynaecological controls. Ascending genital infection with E. colli and Streph.chromogenes led to TOA. In spite of empirical antibiotic treatment, surgical and intensive care supportive therapy of affected organs, patient's condition critically deteriorated until exact fungus specification was made and specific antifungal therapy for Candida krusei with voriconazol was started. After that patient's condition improved. Conclusions Connection between patient's age, IUD use duration and severity of the pelvic inflammatory disease (PID) was seen as multiorgan septic dysfunction with dominant lung failure. Candida pneumonia is rare with non-neutropenic patients. Especially with \"non albicans\" species. We believe Candida krusei infection in ourpatientis related to general weakness and immunocompromised condition because of prolonged and severe PID. Candida krusei infection needs immediate specific antifungal treatment. It was the first Candida krusei infection in our ICU"},{"@xml:lang":"sl","#text":"Pogostost okužb, povzročenih s Candido glabrato in Candido krusei, ki sta boljodporni na flukonazol kot Candida albicans, narašča pri hospitaliziranih bolnikih, še posebej med bolniki v intenzivnih enotah. Posebej nevarne so sistemske okužbe z vrstami Candide. Pljučnica, povzročena z vrstami Candida, najpogosteje Candido albicans, redkeje z ostalimi, je resna okužba, posebej pri imunsko oslabelih bolnikih, in je pogosto smrtna. V prispevku opisujemo primer hude okužbe pljuč s Candido krusei, odporno na flukonazol, pri 42-letni, sicer zdravi bolnici, s počenim tubo-ovarijskim abscesom, posledičnohudo sepso in septičnim šokom. Primarni vzrok abscesa je bila ascendentna okužba rodil z E.colli in Staph. chromogenes, ki je nastala po dolgoletni (17 let) uporabi materničnega vložka (MV) brez rednih ginekoloških pregledov. Kljub operativnemu in intenzivnemu podpornemu zdravljenju prizadetih organov ter večtirnemu empiričnemu antibiotičnemu zdravljenju, vključno s flukonazolom, se je stanje bolnice kritično slabšalo vse do specifikacije gliv in uvedbe specifičnega antimikotičnega zdrav jenja za Candido krusei z vorikonazolom. Po uvedbi tega zdravila se je zdravljenje uspešno zaključilo. Zaključki Povezava med starostjo bolnic, časom uporabe MV in zapletenostjo poteka pelvičnega vnetja (PV) se je pri naši bolnici kazala vseptični prizadetosti vseh organov s prevladujočo prizadetostjo pljuč. Pljučnica, povzročena s Candido, je zelo redek pojav pri nenevtropeničnih bolnikih. Še posebej redka je okužba z vrstami ne-albicans . Okužbo s Candidokrusei pri naši bolnici povezujemo s splošno oslabelostjo in imunsko prizadetostjo ob hudo potekajočem pelvičnim vnetjem (PV) zaradi dolgotrajne uporabe MV. Opisana okužba s Candido krusei zahteva takojšnjo specitično antimikotično zdravljenje. To je bila prva tovrstna okužba v naši intenzivni enoti"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:DOC-P7FENLI0","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:DOC-P7FENLI0"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:DOC-P7FENLI0/7d96f228-9ce8-4dab-a9c5-1af9702489a0/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:DOC-P7FENLI0/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:DOC-P7FENLI0"}}}}