59 KB5631 KB38 KB200020242007Arriazu, RiánsaresCárdenas, ManuelIngelmo, IldefonsoMartín, RocíoPozuelo, José MRodríguez, RosarioSánchez Alberca, AlfredoSantamaría, Luisštevilka:111 straniletnik:26str. 1-11ISSN:1580-3139COBISSID:23912409URN:URN:NBN:SI:doc-LRMF4DYCenDruštvo za stereologijo in kvantitativno analizo slike, Medicinska fakultetaImage analysis and stereologyanalizaAndrogeniAndrogensCytologyDiscriminant AnalysisDiskriminacijska analizaGrowth And DevelopmentImage Processing, Computer-AssistedImmunohistochemistryImunohistokemijaNerve FibersNeurosecretionNevrosekrecijapodganePodgane, WistarProstataProstateRats, WistarSerotoninSlika, obdelava z računalnikomstereologijaŽivčna vlaknaEvolution of neuroendocrine cell population and peptidergic innervation, assessed by discriminant analysis, during postnatal development of the rat prostate|Serotonin immunoreactive neuroendocrine cells and peptidergic nerves (NPY and VIP) could have a role in prostate growth and function. In the present study, rats grouped by stages of postnatal development (prepubertal, pubertal, young and aged adults) were employed in order to ascertain whether age causes changes in the number of serotoninergic neuroendocrine cells and the length ofNPY and VIP fibres. Discriminant analysis was performed in order to ascertain the classificatory power of stereologic variables (absolute and relative measurements of cell number and fibre length) on age groups. The following conclusions were drawn: a) discriminant analysis confirms the androgen-dependence of both neuroendocrine cells and NPYVIP innervation duringthe postnatal development of the rat prostate; b) periglandular innervation has more relevance than interglandular innervation in classifying the rats in age groups; and c) peptidergic nerves from ventral, ampullar and periductal regions were more age-dependent than nerves from the dorso-lateral regionTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaDruštvo za stereologijo in kvantitativno analizo slike