{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-HQJEEMD9/cda8949c-d72b-44db-b502-3f849d9f6869/HTML","dcterms:extent":"27 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-HQJEEMD9/35060597-d30f-457e-93ec-6a908153fa4b/PDF","dcterms:extent":"488 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-HQJEEMD9/fe2649c3-ff8c-4d25-a76b-26241d344526/TEXT","dcterms:extent":"25 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:DOC-HQJEEMD9","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2010","dc:creator":["Morela, Kristina","Morela, Vesna","Pahor, Dušica"],"dc:format":[{"@xml:lang":"sl","#text":"7 strani"},{"@xml:lang":"sl","#text":"letnik:79"},{"@xml:lang":"sl","#text":"str. I-89-I-95"},{"@xml:lang":"sl","#text":"številka:suplement"}],"dc:identifier":["ISSN:1318-0347","COBISSID:3788095","URN:URN:NBN:SI:doc-HQJEEMD9"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"en","#text":"Corneal Topography"},{"@xml:lang":"en","#text":"cross-linking"},{"@xml:lang":"sl","#text":"Izid zdravljenja"},{"@xml:lang":"en","#text":"Keratoconus"},{"@xml:lang":"sl","#text":"Keratokonus"},{"@xml:lang":"sl","#text":"kirurška tehnika"},{"@xml:lang":"sl","#text":"oftalmologija"},{"@xml:lang":"sl","#text":"Oftalmološki kirurški postopki"},{"@xml:lang":"sl","#text":"operativno zdravljenje"},{"@xml:lang":"en","#text":"Ophthalmologic Surgical Procedures"},{"@xml:lang":"sl","#text":"roženica"},{"@xml:lang":"sl","#text":"Roženica, topografija"},{"@xml:lang":"en","#text":"therapy"},{"@xml:lang":"en","#text":"Treatment Outcome"},{"@xml:lang":"sl","#text":"Zdravljenje"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"Srednjeročni rezultati zdravljenja keratokonusa z metodo cross-linking pri 28 očeh z napredovalo obliko keratokonusa| Mild-term results of treatment with corneal collagen cross-linking in 28 eyes with progression of keratoconus|"},"dc:description":[{"@xml:lang":"sl","#text":"Backgraund: Corneal collagen cross-linking by UVA/ riboflavin represents a new treatment modality for patients suffering from progressive keratoconus. Methods: In the retrospective clinical study we showed 28 eyes with progressive keratoconus where we performed corneal cross-linking treatment. Follow up time after the treatment was from 6 to 21 months. The procedure performed was cross-linking treatment with corneal deepithelization 8 mm in diameter, application of riboflavin and UVA irradiation 3mW/cm2. Before and after treatment besides a complete ophthalmologic examination with uncorrected visual acuity (UCVA) and best corrected visual acuity (UCVA) and best corrected visual acuity (BCVA) also listed examinations were performed: corneal computerized topographic examination, pentacam examination where we measured corneal thickness and intraocular pressure(IOP) evaluation. Parameters analyzed were: UCVA, BCVA, corneal thickness, average keratometry readings, spherical equivalent (SE) and amounth of astigmatism. Results: In statistical analysis we proved that in the three parameters analyzed there was statistical significant difference as before treatment: uncorrected visual acuity, best corrected visual acuity and corneal thickness. In other paramethers analyzed-mean keratometry readings, spherical equivalent and amount of astigmatism there was no statistical significant difference in comparison before and after treatment. With the metod of linear regression we prowed that on the best corrected visual acuity after the treatment the most influence was in best corrected visual acuity before treatment and the degree of keratoconus, other parameters before treatment haven't influenced so much on the postoperative best corrected visual acuity. Conclusions: In keratoconus eyes treated with corneal collagen cross-linking result indicate stabilization and improvement. Thus, collagen cross-linking is an effective therapeutically option for progressive keratoconus. This is an ongoing research and longer follow up with higher number of cases are necessary to confirm a definite conclusion"},{"@xml:lang":"sl","#text":"Izhodišča: Metoda Cross-linking z UVA/riboflavinom je nova možnost zdravljenja pri bolnikih z napredovalim keratokonusom. Metode: V retrospektivni raziskavi prikazujemo 28 primerov oči, pri katerih smo ugotovili napredovanje keratokonusa in jih zdravili z metodo cross-linking. Opazovano obdobje je od 6 do 21 mesecev. Operacija je potekala z odstranitvijo epitelne plasti roženice v primeru 8 mm, s kapanjem riboflavina ter nato z obsevanjem z UVA žarki z močjo 3mW/cm2. Pred operacijo in po njej smo poleg splošnega oftalmološkega pregleda naredili naslednje preiskave: meritev vidne ostrine brez korekcije in z njo, meritev očesnega tlaka, topografijo roženice in preiskavo pentacam, s katero smo določili debelino roženice. S statistično analizo smo preučili naslednje parametre: vidno ostrino brez korekcije in z njo, debelino roženice, povprečne vrednosti keratometrije, sferni ekvivalent in vrednosti astigmatizma. Rezultati: S statistično analizo smo ugotovili, da je v treh opazovanih parametrih prišlo do statistično pomembne razlike po zdravljenju, in sicer pri nekorigirani vidni ostrini, korigirani vidni ostrini in debelini roženice. Pri ostalih spremenljivkah, povprečni vrednosti keratometrije, smernem ekvivalentu in vrednosti astigmatizma, pa ni prišlo do statistično pomembne razlike v rezultatih pred zdravljenjem in po njem. Z metodo linearne regresije smo pokazali, da najbolj od vseh spremenljivk na korigirano vidno ostrino po operaciji vpliva korigirana vidna ostrina pred operacijo, takoj za tem pa stopnja keratokonusa. Ostali parametri pred operacijo niso bistveno vplivali na korigirano vidno ostrino po operaciji. V pooperativnem poteku smo imeli en primer, ko je terapevtska kontaktna leča izpadla iz očesa in je prišlo do prehodnega vnetja roženice, ki smo ga pozdravili brez poznih posledic za bolnico. Zaključki: V primerih oči z napredovalim keratokonusom smo pri zdravljenju z metodo cross-linking ugotovili, da rezultati nakazujejo stabilizacijo oz. ustavitev napredovanja keratokonusa v časovnem obdobju največ 21 mesecev po operaciji. Gre za klinično študijo, ki je v teku in v kateri bomo sledili bolnike v daljšem opazovanem obdobju. V študijo bomo vključili še nove bolnike, da bomo dobili večje število primerov, ki jih bomo sledili daljše obdobje, kar je potrebno, da bomo lahko stvarno ovrednotili uspešnost zdravljenja"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:DOC-HQJEEMD9","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:DOC-HQJEEMD9"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:DOC-HQJEEMD9/35060597-d30f-457e-93ec-6a908153fa4b/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:DOC-HQJEEMD9/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:DOC-HQJEEMD9"}}}}