104 KB6 KB199220251997Klocker, J...Raunik, W...Sabitzer, H...Schumer, J...Wieser, S...številka:2letnik:31str. 171-172ISSN:1318-2099COBISSID_HOST:7176665URN:URN:NBN:SI:doc-H81M3IYEenCroatian Medical Association - Croatian Society of RadiologySlovenian Medical Society - Section of RadiologyRadiology and oncology (Ljubljana)Carcinoma, squamous cellCisplatinDrug therapyHead and neck neoplasmsHyaluronidaseRadiotherapyTreatment outcomeVindesineCombined application of cisplatin, vindesine, hyaluronidase and radiation for treatment of advanced squamous cell carcinoma of the head and neck|Forty eight patients with advanced head and neck tumours were treated with irradiation and concomitant chemotherapy with cisplatin, vindesine and hyaluronidase. The disease-free survival rate at 5 years was 47%. The toxic effects were mucositis (48 patients), nausea (25 patients - in 6 patients vomiting), bone marrow depression (15 patients), and peripheral neuropathy (14patients). The results warrant a randomised trialTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaOnkološki inštitut Ljubljana