33 KB454 KB27 KB192920262011Hazabent, MarkoHorvat, MatjažIvanecz, ArpadJagrič, TomažPotrč, Stojanštevilka:1letnik:80str. 25-32ISSN:1318-0347COBISSID:27863001URN:URN:NBN:SI:doc-G81K0TPGslSlovensko zdravniško društvoZdravniški vestnikAdultGastrectomyGastrektomijaNeoplasm StagingNovotvorba, stadijOdraslipreživetjePreživetje, analizarak (medicina)Stomach NeoplasmsSurvival AnalysistherapyzdravljenježelodecŽelodec, novotvorbeZnačilnosti in izid zdravljenja mlajših bolnikov z rakom želodca v Sloveniji| Characteristics and prognosis of young patients with gastric cancer in Slovenia|Results: We found significant differences in their ASA scores (p < 0.001): the majority of patients in the younger group scored ASA I (93 %), while most of the patients in the older group scored ASA II or III (72 %). In the youngergroup there were significantly more Lauren diffuse-type carcinomas (63 % versus 36 %; P = 0.007), total gastrectomies (79 % versus 55 %; P = 0.003), and harvested lymph nodes (26 19 versus 21 14; P = 0.02). There were no statistically significant differences in curative resections (86 % versus 85 %), TNM stage distribution and in the rate of perioperative surgical and non-surgical morbidity and mortality. Actuarial 5-year survival rates for the younger and the older groups were 43.8 % and 34.1 % respectively (P = 0.05). Actuarial 10-year survival rates for the younger and the older groups were 37 % and 23.7 % respectively (P = 0.05). The factors associated with adverse 5-year survival in multivariate analysis were higher TNM UICC stage, non-curative resection, higher ASA scores, and N2-3 lymph node metastases. Conclusions: Differences in the ASA scores between the two groups were expected. A second feature was the predominance of the Lauren diffuse type in the younger group. A higher portion of total gastrectomies and harvested lymphnodes were the consequences of the more aggressive surgical approach in younger patients. Survival was better in the younger group of patients, although the outcome is probably more related to stage of the disease at diagnosis than to ageTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo