23 KB196 KB21 KB192920262009Pernat, AndrejŠinkovec, Matjažletnik:78številka:9str. 457-461ISSN:1318-0347COBISSID:26096089URN:URN:NBN:SI:doc-86UAXV09enSlovensko zdravniško društvoZdravniški vestnikAtrial Fibrillationatrijska fibrilacijacardiovascular diseaseCatheter AblationFollow-Up Studieskardiovaskularne bolezniKateterska odstranitevPreddvorna fibrilacijaradiofrekvenčna ablacijaSledilne študijetherapyTreatment OutcomezdravljenjeZdravljenje, izidFollow-up after lasso-guided irrigated tip radiofrequency catheter ablation in paroxysmal and persistent atrial fibrillation| Klinični izidi po radiofrekvenčni ablaciji paroksizmalne in perzistentne atrijske fibrilacije s pomočjo lasokatetra in ablacijskega katetra s hlajeno konico|Aims We evaluated clinical outcome of segmental/circumferential pulmonary vein(PV) isolationand linear defragmentation procedure in our first series of patients with paroxy or persistent atrial fibrillation (PAF/PEAF). The freedomfrom symptomatic AF/flutter/ tachycardia recurrences with patients off antiarrhythmic treatment (AAD) was primary endpoint of the procedure. Methods Consecutive patients with highly symptomatic PAF/PEAF and AAD failure were prospectively recruited from September 2003 to June 2007. Patients < 70 years with left ventricular ejection fraction > 40 % and left atrial diameter < 50mmwere included. During the first procedure 2-4 PVs, non-PV foci, and/or flutter isthmus (FI) were targeted. If arrhythmia recurred, conducting gaps toPVs and FI are ablated after blanking period of > 3 months. In patients withPEAF, fast fragmented/complex electrograms were ablated in a linear fashion, connecting upper PV ostia and/or PV ostia with proximal anatomical structures. Only FI line was tested for completeness of block. The irrigated-tip radiofrequency ablation catheter and Lasso catheter (Biosense-Webster) were used after standard transseptal approach with X-ray fluoroscopy guidance. The suspected arrhythmia recurrences were evaluated by series of ECG/Holter recordings. Results. Fifty-eight patients, 43 men, average age 50 years, range 19-69, including 24(41 %) with PEAF, were enrolled. In these patients, 113 procedures were performed: single study in 20, 2 in 24, 3 in 11, and 4 in 3 patients, respectively. Complications occurred in 5 patients including tamponade in 2, acute effusion in 1, and inadvertened pericardial punction in 2. No PV stenosis, esophageal injury, or stroke were detected clinically during 16-month (4-47) follow-up. (Abstract truncated at 2000 characters)TEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaSlovensko zdravniško društvo