260 KB37 KB200220262024Drešček, MarkoDrešček, MarkoHomar, VesnaMiroševič, ŠpelaOrešković, StjepanRifel, JanezŠvab, Igorštevilka:4letnik:63str. 180-187ISSN:0351-0026DOI:10.2478/sjph-2024-0024COBISSID_HOST:208968963URN:URN:NBN:SI:doc-60PB6EC1enNacionalni inštitut za javno zdravjeZdravstveno varstvodrug therapyfarmakoterapijaodvisnost od nikotinaopuščanje kajenjasmoking cessationtobacco usetobacco use disorderuporaba tobakaSmokers' characteristics associated with successful smoking cessation undergoing pharmacotherapy in Slovenia| Značilnosti kadilcev, povezane z uspešnim opuščanjem kajenja s farmakoterapijo v Sloveniji|Introduction Tobacco use is a major global health problem, contributing to premature death and disability. In Slovenia, the prevalence of smoking is higher than the EU average, emphasizing the need for effective tobacco control measures. The aim of this study was to identify the characteristics of patients most likely to benefit from pharmacotherapy for smoking cessation. Methods We performed cross-sectional analysis of factors associated with successful smoking cessation using pharmacotherapy for Slovenian smokers. A total of 176 (24.6%) smokers with an average age of 50 years agreed to receive pharmacotherapy for their smoking cessation attempt and were enrolled in the study. Participants were followed up at 4-week intervals during treatment and for 24 weeks after completion of pharmacotherapy. Results Attempts to quit smoking with prescription medications were successful in 24.4% of those willing to try. Female smokers, older persons, those with more children, with a lower self-perception of health, a higher number of cigarettes per day and a higher nicotine dependence were more likely to attempt to quit smoking. However, the strongest predictors of smoking cessation success were lower nicotine dependence, which was tested using the Fagerström test for nicotine dependence, and higher adherence to pharmacotherapy. Conclusion Nicotine dependence and adherence to pharmacotherapy are the strongest predictors of a successful smoking cessation attempt. Identification of potential responders, prescription of pharmacotherapy and follow-up are applicable in the primary healthcare settingUvod: Kajenje je pomemben svetovni zdravstveni problem, ki prispeva k prezgodnji smrti in invalidnosti. Slovenija ima višjo razširjenost kajenja v primerjavi s povprečjem EU, kar poudarja potrebo po učinkovitih ukrepih za nadzor tobaka. Namen te študije je bil ugotoviti značilnosti bolnikov, ki jim bo farmakoterapija pri opuščanju kajenja najverjetneje koristila. Metode: Opravili smo presečno analizo dejavnikov, povezanih z uspešno opustitvijo kajenja z uporabo farmakoterapije pri slovenskih kadilcih. 176 kadilcev s povprečno starostjo 50 let se je strinjalo z uporabo farmakoterapije za poskus opustitve kajenja in so bili vključeni v študijo. Udeležence smo spremljali v 4-tedenskih intervalih med zdravljenjem in 24 tednov po zaključku farmakoterapije. Rezultati: Poskus opustitve kajenja z zdravili na recept je bil uspešen pri 24,4 % kadilcev. Kadilke, starejše osebe, z več otroki, z nižjo samooceno zdravja, večjim številom pokajenih cigaret na dan in večjo odvisnostjo od nikotina so pogosteje poskušale opustiti kajenje. Vendar pa je bilo ugotovljeno, da sta manjša odvisnost od nikotina, preizkušena s Fagerströmovim testom za odvisnost od nikotina, in višja adherenca farmakoterapiji najmočnejša napovedna dejavnika uspeha pri opuščanju kajenja. Zaključek: Odvisnost od nikotina in upoštevanje farmakoterapije sta najmočnejša napovedna dejavnika uspešnega poskusa opustitve kajenja. Tako identifikacija možnih odzivnikov in predpisovanje farmakoterapije kot nadaljnje spremljanje se lahko izvajajo v osnovnem zdravstvenem varstvuTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaNacionalni inštitut za javno zdravje