{"?xml":{"@version":"1.0"},"edm:RDF":{"@xmlns:dc":"http://purl.org/dc/elements/1.1/","@xmlns:edm":"http://www.europeana.eu/schemas/edm/","@xmlns:wgs84_pos":"http://www.w3.org/2003/01/geo/wgs84_pos","@xmlns:foaf":"http://xmlns.com/foaf/0.1/","@xmlns:rdaGr2":"http://rdvocab.info/ElementsGr2","@xmlns:oai":"http://www.openarchives.org/OAI/2.0/","@xmlns:owl":"http://www.w3.org/2002/07/owl#","@xmlns:rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","@xmlns:ore":"http://www.openarchives.org/ore/terms/","@xmlns:skos":"http://www.w3.org/2004/02/skos/core#","@xmlns:dcterms":"http://purl.org/dc/terms/","edm:WebResource":[{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-5GO6AX8P/60b55b81-25fc-4f01-9a5f-8eea81409d73/PDF","dcterms:extent":"62 KB"},{"@rdf:about":"http://www.dlib.si/stream/URN:NBN:SI:DOC-5GO6AX8P/57a223b8-f67f-44e1-a90c-3253073d5e83/TEXT","dcterms:extent":"12 KB"}],"edm:TimeSpan":{"@rdf:about":"1929-2026","edm:begin":{"@xml:lang":"en","#text":"1929"},"edm:end":{"@xml:lang":"en","#text":"2026"}},"edm:ProvidedCHO":{"@rdf:about":"URN:NBN:SI:DOC-5GO6AX8P","dcterms:isPartOf":[{"@rdf:resource":"https://www.dlib.si/details/urn:nbn:si:spr-a30mfzkp"},{"@xml:lang":"sl","#text":"Zdravniški vestnik"}],"dcterms:issued":"2004","dc:creator":["Černelč, Peter","Faganel Kotnik, Barbara"],"dc:format":{"@xml:lang":"sl","#text":"str. I-163-I-164"},"dc:identifier":["ISSN:1318-0347","COBISSID_HOST:17684441","URN:URN:NBN:SI:doc-5GO6AX8P"],"dc:language":"sl","dc:publisher":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"dc:subject":[{"@xml:lang":"sl","#text":"Aged"},{"@xml:lang":"sl","#text":"Autoantibodies"},{"@xml:lang":"sl","#text":"Avtoprotitelesa"},{"@xml:lang":"sl","#text":"Factor VIII"},{"@xml:lang":"sl","#text":"Faktor VIII"},{"@xml:lang":"sl","#text":"Hemophilia"},{"@xml:lang":"sl","#text":"Starostniki"},{"@xml:lang":"sl","#text":"Subarachnoid Hemorrhage"},{"@xml:lang":"sl","#text":"Subarahnoidna krvavitev"},{"@xml:lang":"sl","#text":"Surgery"},{"@xml:lang":"sl","#text":"Therapeutic Use"}],"dcterms:temporal":{"@rdf:resource":"1929-2026"},"dc:title":{"@xml:lang":"sl","#text":"Pojav protiteles za faktor VIII pri starejšem bolniku z lahko obliko hemofilije A| The appearance of the inhibitors to factor VIII in an elder patient with mild haemophilia A|"},"dc:description":[{"@xml:lang":"sl","#text":"Background. The inhibitors to F Vlll are unusual in case of a mild haemophiliabecause the replacement therapy is seldom necessary. In case of severe trauma, when prolonged replacement therapy of F VIII is needed, the appearance of the inhibitors is more frequent The mild form of the disease becomes a severe one and the haemorrhages are frequent. Patient and methods. In case of outpatient with mild form of haemophilia, the inhibitors to F VIII developed after prolonged replacement therapy for treatment of subdural haemorrhage. In the article we describe recurrent haemorrhages and treatement of them with FEIBA and rF Vlla. Conclusions. Due to poor compliance of an elder patient we didn't decide to treat the inhibitors for F VIII actively"},{"@xml:lang":"sl","#text":"Izhodišča. Protitelesa za F Vlll se pri bolniku z lahko obliko hemofilije zeloredko pojavijo, saj je nadomestno zdravljenje s F Vlll običajno le redko potrebno. V primeru hujše poškodbe, ko je potrebno dolgotrajnejše zdravljenje s F Vlll, pa se protitelesa lahko pojavijo. Tako lahka oblika bolezni postane težka in poteka s ponavljajočimi se krvavitvami. Bolniki in metode. Pri našem bolniku z lahko obliko bolezni so se protitelesa za F VIII pojavila po daljšemnadomestnem zdravljenju subduralne krvavitve. Opisujemo ponavljajoče sekrvavitve in zdravljenje teh s FEIBO in rF Vlla. Zaključki. Za aktivno zdravljenje protiteles za FVIll se zaradi slabšega sodelovanja starejšega bolnika nismo odločili"}],"edm:type":"TEXT","dc:type":[{"@xml:lang":"sl","#text":"znanstveno časopisje"},{"@xml:lang":"en","#text":"journals"},{"@rdf:resource":"http://www.wikidata.org/entity/Q361785"}]},"ore:Aggregation":{"@rdf:about":"http://www.dlib.si/?URN=URN:NBN:SI:DOC-5GO6AX8P","edm:aggregatedCHO":{"@rdf:resource":"URN:NBN:SI:DOC-5GO6AX8P"},"edm:isShownBy":{"@rdf:resource":"http://www.dlib.si/stream/URN:NBN:SI:DOC-5GO6AX8P/60b55b81-25fc-4f01-9a5f-8eea81409d73/PDF"},"edm:rights":{"@rdf:resource":"http://creativecommons.org/licenses/by-nc/4.0/"},"edm:provider":"Slovenian National E-content Aggregator","edm:intermediateProvider":{"@xml:lang":"en","#text":"National and University Library of Slovenia"},"edm:dataProvider":{"@xml:lang":"sl","#text":"Slovensko zdravniško društvo"},"edm:object":{"@rdf:resource":"http://www.dlib.si/streamdb/URN:NBN:SI:DOC-5GO6AX8P/maxi/edm"},"edm:isShownAt":{"@rdf:resource":"http://www.dlib.si/details/URN:NBN:SI:DOC-5GO6AX8P"}}}}