242 KB70 KB0 KB199420252021Bregar, BrankoČulić, ArminMacur, Mirnaštevilka:4letnik:55str. 274–286DOI:10.14528/snr.2021.55.4.3063ISSN:1318-2951COBISSID_HOST:90073347URN:URN:NBN:SI:doc-3KJ0RLVCslZbornica zdravstvene negeObzornik zdravstvene negecanabiskanabisKonopljamedical useMedicinamedicinska rabatreatmentzdravljenjeRaba konoplje v medicinske namene| an integrative literature review| integrativni pregled literature| Medical use of cannabis|Introduction: In 2017, cannabis was approved for medical use in Slovenia. Cannabis has more than 140 compounds of which the most important are cannabidiol and tetrahydrocannabinol because of their healing powers. The aim of review is to investigate the medical use of cannabis.Methods: An integrative literature review was conducted in the PubMed digital database, the online search engine Google Scholar and the COBISS bibliographic system. Keywords used in the search were: "marihuana AND medical use", "cannabis AND medical use" and "raba konoplje v medicinske namene". The limitations of the search were the period of publication of the literature (2008–2019), free access to peer-reviewed scholarly articles, and the English or Slovenian language. A thematic analysis of the material was used to review the literature.Results: 29 articles were selected for the final analysis. 52 codes were identified, grouped into 4 categories: (1) treatment with cannabis, (2) properties of cannabis, (3) effects of cannabidiol, (4) effects of tetrahydrocannabinol.Discussion and conclusion: Cannabis has been used for medical purposes for several thousand years. Today, it is mainly used for the treatment of the following medical conditions: asthma, diabetes, epilepsy, cancer, Parkinson's disease, Alzheimer's dementia and multiple sclerosis. In Slovenia, cannabis has been removed from the list of most dangerous drugs, however, the path to being approved for the use for medical purposes will be challengingUvod: Slovenija je leta 2017 spremenila uredbo o razvrstitvi prepovedanih drog in omogočila uporabo konoplje v medicinske namene. Konoplja ima več kot 140 kanabinoidnih spojin, med katerimi sta najbolj izpostavljeni kanabidiol in tetrahidrokanabinol, saj imata potencial za zdravljenje bolezni. Namen pregleda je raziskati rabo konoplje v medicinske namene.Metode: Izveden je bil integrativni pregled literature v digitalni zbirki podatkov PubMed, spletnem iskalniku Google učenjak in vzajemnemu bibliografskemu sistemu COBISS s pomočjo besednih zvez: »cannabis AND medical use«, »marihuana AND medical use« in »raba konoplje v medicinske namene«. Omejitve iskanja so bile: obdobje objave literature (2008–2019), prost dostop do recenziranih strokovnih in znanstvenih člankov ter literatura v angleškem ali slovenskem jeziku. Za pregled literature je bila uporabljena tematska analiza prebranega gradiva.Rezultati: Za pregled literature je bilo za končno analizo primernih 29 člankov. Identificiranih je bilo 52 kod, združenih v štiri teme: (1) zdravljenje s konopljo, (2) lastnosti konoplje, (3) delovanje kanabidiola, (4) delovanje tetrahidrokanabinola.Diskusija in zaključek: Konoplja se že tisočletja uporablja v medicinske namene. Danes jo v svetu uporabljajo predvsem za zdravljenje naslednjih bolezni: astme, diabetesa, epilepsije, raka, Parkinsonove bolezni, Alzheimerjeve demence, multiple skleroze. V Sloveniji je konoplja odstranjena s seznama najbolj nevarnih drog, a do njene rabe v medicinske namene je zahteven procesTEXTznanstveno časopisjejournalsSlovenian National E-content AggregatorNational and University Library of SloveniaZbornica zdravstvene in babiške nege Slovenije - Zveza strokovnih društev medicinskih sester, babic in zdravstvenih tehnikov Slovenije