MOJ PRIROČNIK

IN DNEVNIK

ZA ZDRAVLJENJE

Z NINTEDANIBOM





Kazalo

Uvod

• Uvod ..................................................................................................................................................3

Zdravilo nintedanib se uporablja pri zdravljenju žleznega raka pljuč (adenokarcinom), pogoste oblike raka na pljučih, ko trenutno zdravljenje ni več primerno. 1

• Kaj zdravniki upoštevajo, ko se odločajo o obliki zdravljenja? ....................................4

S pomočjo te knjižice se lahko bolje poučite o tem, kako zdravilo deluje in kaj

• Kaj na povem zdravniku, preden začnem jemati zdravilo nintedanib ......................6

pričakovati, medtem ko ga jemljete.

• Jemanje zdravila nintedanib .....................................................................................................8

• Kateri so najpogostejši možni neželeni učinki zdravila? .............................................. 13

• Pogosti možni neželeni učinki .............................................................................................. 14

• Pogosti možni resni neželeni učinki .................................................................................... 18

• Dodatna pomoč ......................................................................................................................... 21

• Viri .................................................................................................................................................... 22

2





Delovanje zdravila nintedanib

• Novo zdravilo nintedanib se vedno jemlje v kombinaciji s kemoterapijo (docetaksel). 1 To je zato, ker ti dve zdravili delujeta na različne načine in se med Kaj zdravniki upoštevajo, ko se

seboj dopolnjujeta:

- nintedanib je “anti-angiogenetsko” zdravilo: upočasnjuje rast tumorjev s odločajo o obliki zdravljenja?

tem, da preprečuje njihovo prekrvavitev. 1, 5

• Zdravila za zdravljenje rakavih obolenj bolniku pomagajo živeti dlje, upočasnjujejo rast tumorja in zmanjšujejo simptome, ne da bi pri tem preveč vplivali na bolnikovo sposobnost za opravljanje običajnih vsakodnevnih aktivnosti. 2

• Zdravnik vam je ponudil zdravilo nintedanib, saj meni, da je glede na vaše splošno Iz obstoječih žil

zdravstveno stanje primerno za zdravljenje vaše bolezni.2

nastajajo nove

Zdravilo nintedanib

(angiogeneza), ki

preprečuje rast novih

oskrbujejo tumor

žil (antiangiogeneza).

Oblika raka, ki se zdravi z zdravilom nintedanib in vaš primer s hranili, ki jih ta

TUMOR

potrebuje za rast

in razvoj.

• Zboleli ste za žleznim rakom pljuč (adenokarcinom), eno najpogostejših oblik raka na pljučih, ki je tudi sicer eno najpogostejših rakavih obolenj. 3, 4

• Med sorodnimi podtipi pljučnih rakov se ravno žlezni rak pljuč najbolje odziva na zdravljenje, kar pomeni, da so napovedi uspeha zdravljenja. 2

- Kemoterapija, kot je docetaksel, pa neposredno uničuje rakaste celice. 2

• Zdravilo nintedanib se je izkazalo za še posebej učinkovito pri tistih bolnikih, pri katerih dosedanje zdravljenje ni več učinkovito. 1, 5

• Kombinacija teh dveh zdravil napada vašo bolezen na dva različna načina hkrati.

Novo upanje, ki ga prinaša zdravilo nintedanib

Koristi, ki jih prinaša zdravilo nintedanib

• Zadnjih deset let si zdravstvena in raziskovalna skupnost prizadevata odkriti nova

• Obsežna raziskava je potrdila varnost in učinkovitost zdravila nintedanib pri zdravila, ki bi zmanjšala velikost tumorjev in upočasnila napredovanje bolezni ter bolnikih z žleznim rakom pljuč.

hkrati omogočala bolnikom kar se da normalno vsakodnevno življenje. 5

Če želimo doseči optimalno zdravljenje, je treba zdravilo jemati v skladu z

• Eno tovrstnih novih zdravil je nintedanib. 1, 5

navodili. Več o tem preberite v nadaljevanju.

4





• Zdravnika morate obvestiti, če jemljete: 1

- zdravila proti:

- glivičnim okužbam (antimikotiki)

- bakterijskim okužbam (antibiotiki)

- tuberkulozi (TB)

- epilepsiji

- redčenju krvi

- Zdravila rastlinskega izvora proti:

- depresiji (šentjanževka)

• Če niste prepričani, ali katero od vaših zdravil sodi na zgornji seznam, se o tem posvetujte z zdravnikom ali farmacevtom.

• Morda vam bo lažje, da napišete seznam vseh zdravil, ki jih jemljete, in ga pokažete zdravniku ali farmacevtu.

Zdravnika obvestite o drugih zdravstvenih stanjih

• Podobno kot druga zdravila tudi nintedanib ni primerno za vsakogar.

• Zdravnika morate obvestiti o vsakršnih drugih motnjah ali boleznih, ki jih imate, ter stanjih (npr. če imate probleme z jetri ali krvavitvami, če ste bili nedavno Kaj na povem zdravniku, preden

operirani, če se je rak razširil na možgane, če ste alergični na arašide ali sojo, če ste noseči, dojite ali nameravate zanositi). 1

začnem jemati nintedanib?

Tu so najpomembnejši vidiki, ki jih je treba upoštevati pred začetkom zdravljenja. 1

Nosečnost

• Pred začetkom zdravljenja je treba opraviti test nosečnosti. 1

Zdravnika obvestite o tem, katera zdravila jemljete

• V času jemanja zdravila je treba nosečnost preprečiti. 1

• Pomembno je, da zdravnika obvestite o vseh zdravilih, ki jih jemljete, vključno

• Ženske, ki bi utegnile zanositi, morajo uporabljati učinkovito kontracepcijo, vključno s pregradno metodo kot dodatno obliko z zdravili rastlinskega izvora in zdravilih brez recepta. Določena zdravila namreč kontracepcije, in sicer med in vsaj 3 mesece po koncu jemanja zdravila lahko povzročijo neželeno medsebojno delovanje, če se jih jemlje skupaj z vašo nintedanib in kemoterapije. 1

terapijo, spet druga pa lahko ovirajo ustrezen potek zdravljenja .1

• Med zdravljenjem je treba dojenje prekiniti. 1

6





Jemanje zdravila nintedanib

Kako naj jemljem zdravilo nintedanib

• Vzemite 2 kapsuli zdravila nintedanib zjutraj (pri zajtrku) in še 2 kapsuli zvečer

• Običajni odmerek zdravila nintedanib je 200 mg zjutraj in 200 mg zvečer. 1

(pri večerji), idealno v razmaku 12 ur, razen če drugače predpiše zdravnik. 1

zjutraj

zvečer

Zajtrk

Večerja





Običajni odmerek

2 x 100 mg

2 x 100 mg

12-urni razmak

• Zdravnik lahko odmerek prilagodi, če meni, da je to potrebno zaradi sopojavov 2 kapsuli

2 kapsuli

in prilagojen odmerek ne bo vplival na učinkovitost zdravljenja zdravila nintedanib. 1

• Najbolje je, da zdravilo vsako jutro in večer vzamete ob isti uri. 1

• Če zdravnik prilagodi odmerek, se število kapsul, ki jih morate vzeti, lahko spremeni iz dveh na samo eno zjutraj in eno zvečer. 1

• Zdravilo nintedanib je priporočljivo jemati med

Prvo zmanjšanje





obrokom (ali takoj po jedi) in skupaj

odmerka

1 x 150 mg

1 x 150 mg

s polnim kozarcem vode. 1

• Kapsule pogoltnite cele, ne da bi jih žvečili,

drobili ali rezali. 1

S polnim

Med

Drugo zmanjšanje





kozarcem vode

obrokom

odmerka

1 x 100 mg

1 x 100 mg

POMEMBNO: Če želimo doseči optimalno zdravljenje, je treba zdravilo POMEMBNO: Vašega odmerka morda ni potrebno prilagoditi; nintedanib jemati v skladu z navodili zdravnika. 1

vselej upoštevajte priporočila zdravnika.

8





Jemanje zdravila nintedanib

Kdaj naj jemljem zdravilo nintedanib?

Koliko časa naj jemljem zdravilo nintedanib?

• Zdravilo nintedanib se jemlje vsak dan, razen na dan, ko prejmete kemoterapijo.

• Po končanih vseh ciklih kemoterapije vam bo zdravnik verjetno svetoval, da (običajno na 21 dni). 1

zdravilo nintedanib še naprej jemljete vsak dan. 1

• Priporočljivo je, da zdravilo jemljete toliko časa, dokler je učinkovito in nima PRVIH 21 DNI

NASLEDNJIH 21 DNI

sopojavov, ki jih ni moč prenašati. 1

Kako naj shranjujem zdravilo nintedanib?

V BOLNIŠNICI

DOMA

V BOLNIŠNICI

DOMA

• Kapsule zdravila nintedanib shranjujte na temperaturi do 25°C. 1

1. dan

od 2. do 21. dne

1. dan

od 2. do 21. dne

• Kapsule shranjujte v originalni embalaži in izven dosega otrok. 1

kemoterapija

kapsule zdravila

kemoterapija

kapsule zdravila

infuzija ne vzamem

nintedanib vzamem

infuzija ne vzamem

nintedanib vzamem

kapsul zdravila

2-krat/dan

kapsul zdravila

2-krat/dan

nintedanib

nintedanib

POMEMBNO: Zdravila nintedanib ne smete vzeti ob dnevih, ko POMEMBNO: Če niste prepričani, kdaj morate vzeti zdravilo, se o prejmete kemoterapijo. Takrat izpustite oba odmerka zdravila.

tem posvetujte z zdravnikom ali medicinsko sestro.

Običajni odmerek ponovno vzemite naslednje jutro. 1

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Kateri so najpogostejši možni

neželeni učinki zdravila?

Kaj naj naredim, če po zaužitju zdravila bruham?

• Zdravila za zdravljenje raka lahko povzročijo neželene učinke, vendar se na zdravljenje vsak bolnik odziva drugače. 1

• Če po zaužitja zdravila bruhate, ne smete vzeti nadomestnega odmerka. Naslednji odmerek vzemite ob običajni predvideni uri.

• Najpogostejše neželene učinke kemoterapije najbrž že poznate: znižana koncentracija levkocitov, utrujenost, driska, slabost, zmanjšan apetit, bruhanje,

• Če se bruhanje nadaljuje, o tem obvestite zdravnika.

povišana telesna temperatura, boleči, otrpel in/ali ščemeč občutek v prstih rok in nog (periferna nevropatija), vnetje sluznic prebavnega trakta (mukozitis). 6

Kaj naj naredim, če pozabim vzeti zdravilo?

• Ko se kemoterapiji pridruži zdravilo nintedanib, se lahko določeni neželeni učinki

• Če pozabite vzeti zdravilo, vzemite naslednji odmerek ob običajni predvideni uri.

kemoterapije pojavljajo pogosteje; med njimi so najpogostejši driska, slabost in znižana koncentracija levkocitov .1, 5

• Ne povečujte običajnega dnevnega odmerka, da bi nadoknadili zamujeni odmerek.

• Pojavijo se lahko tudi nekateri neželeni učinki, ki so povezani z zdravilom nintedanib, npr. zvišani jetrni encimi (abnormalni krvni testi).

• Ne vzemite obeh dnevnih odmerkov zdravila hkrati. Če ste pomotoma vzeli večji odmerek od predpisanega, pokličite zdravnika ali farmacevta. 1

• Drisko in slabost je večinoma mogoče urediti z jemanjem tablet ali s spremembo malih vsakdanjih stvari, kot je npr. hrana, ki jo uživate. Več o tem preberite v nadaljevanju.

• Zaradi določenih neželenih učinkov lahko zdravnik prilagodi odmerek zdravila nintedanib ali kemoterapije, začasno prekine ali popolnoma preneha z zdravljenjem. 1

POMEMBNO: V primeru neželenih učinkov se posvetujte z zdravnikom. Ne spreminjajte odmerka in ne prenehajte z zdravljenjem brez predhodnega posvetovanja z zdravnikom. 1

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Dodatni nasveti, kako ukrepati proti driski: 1,7

Pogosti možni neželeni učinki

Kako ukrepati proti driski?

Pijte veliko tekočine

• Da bi preprečili izsušenost, pijte veliko vode in drugih bistrih tekočin (vsaj 3 litre na dan). Driska lahko vodi v izsušenost, ki lahko povzroči Bodite pozorni na

glavobole, migreno in izgubo koncentracije, če pa postane resna, se lahko

• spremembe iztrebljanja (povečana frekvenca iztrebljanja mehkega zgodi, da mora bolnik v bolnišnico.

ali tekočega blata)

Jejte preprosto

Kontaktirajte osebnega zdravnika …

• Določena hrana lahko drisko še poslabša. Poskušajte jesti preprosto hrano, kot so riž, rezanci, banane, bel kruh, bele ribe, piščanec in puran (brez kože).

• ko drisko dobite prvič (odvajate več kot 4krat dnevno tekoče, vodeno blato), Zdravstveni tim vam lahko predpiše dodatne spremembe prehrane.

• če se počutite zelo slabo in driska ovira vaše vsakdanje aktivnosti,

• Izogibajte se kofeinu, alkoholu, mlečnim izdelkom, maščobam, vlakninam, pomarančnemu soku, slivovemu soku in začinjeni hrani.

• če drisko spremlja kateri od naslednjih simptomov: bolečine ali krči v trebuhu, povišana telesna temperatura, mrzlica z drgetanjem, kri v blatu, nezmožnost pitja

• Jejte manjše obroke, večkrat na dan.

tekočin in/ali gost in temen urin,

• Ne jemljite odvajal, razen če vam zdravnik predpiše drugače.

• če drisko urejate v skladu z navodili zdravnika cel dan in je število iztrebljanja še vedno za 4 ali več večje od običajnega.

Vzdržujte higieno

Kako se zdravi?

• Driska vsebuje škodljive bakterije, ki lahko povzročijo boleče poškodbe kože.

• Zdravnik ali medicinska sestra vam lahko svetuje, da imejte vselej pri sebi

• Da te bakterije odstranite, si rektalni predel redno umivajte tablete proti driski (npr. loperamid), da jih boste lahko vzeli takoj, ko bo to s toplo vodo.

potrebno. Vedno upoštevajte navodila zdravnika. 1

• Redno si umivajte tudi roke.

• Zdravnik lahko zaradi driske vseeno prilagodi in/ali prekine zdravljenje z zdravilom nintedanib. Ne spreminjajte odmerka in ne prenehajte z zdravljenjem brez predhodnega posvetovanja z zdravnikom ali medicinsko sestro. 1

14





Dodatni nasveti, kako ukrepati proti slabosti in bruhanju 1,8,9

Kako ukrepati proti slabosti in bruhanju?

Izogibajte se močnim vonjavam

• Močne vonjave lahko slabost in bruhanje poslabšajo, zato se jim izogibajte Bodite pozorni na

v celoti.

• občutek, ko mislite, da boste bruhali (slabost), in dejansko bruhanje

• Uporabljajte dezodorante in mila brez vonja.

Kontaktirajte osebnega zdravnika…

Jejte preudarno

• če slabost ali bruhanje traja več kot 24 ur,

• Bogata in težka hrana lahko poslabša občutek slabosti. Jejte manjše

• če slabost ali bruhanje spremlja kateri od naslednjih simptomov: obroke večkrat na dan.

hude bolečine v trebuhu, povišana telesna temperatura, kri v bruhanju,

• Izbirajte beljakovinsko bogato (npr. meso, ribe, piščanec) in

• če ne morete jesti ali piti 12 ur ali več,

visokokalorično hrano (npr. oreški, testenine ali žitarice), s katero boste ostati pri močeh.

• če se pojavi kateri od naslednjih simptomov izsušenost: prekomerna

• Če se le da, se izogibajte začinjeni, mastni, ocvrti in kisli hrani.

žeja, suha usta, znižana pogostost uriniranja, temno obarvan urin, šibkost, omotica,

• če pa je bruhanje nenadzorovano, svoj zdravstveni kontakt pokličite nemudoma.

Pijte počasi

• Tekočine pijte počasi in vsaj eno uro pred ali po obroku namesto med jedjo.

Kako se zdravi?

• Zdravnik ali medicinska sestra vam lahko predpiše tablete proti slabosti/bruhanju.

Če ne učinkujejo, se obrnite na svojega zdravnika ali medicinsko sestro. 1

• Pogosto lahko slabost in bruhanje uredimo z zgodnjim ukrepanjem. Vendar Vzemite si čas za počitek

pa lahko zdravnik vseeno prilagodi in/ali prekine zdravljenje z zdravilom

• Nekateri bolniki najdejo olajšanje v alternativnih praksah, kot je nintedanib. Ne spreminjajte odmerka in ne prenehajte z zdravljenjem brez sproščanje, dopolnilna terapija (refl eksologija, masaža) ali svetovanje predhodnega posvetovanja z zdravnikom ali medicinsko sestro. 1, 8

(psihološka podpora).

16





Dodatni nasveti, kako

že v začetku preprečiti okužbe 10

Pogosti možni resni neželeni

Vzdržujte higieno

učinki

• Roke si umivajte redno, še posebej pred jedjo ter po veliki in mali potrebi.

• Ko delate na vrtu ali čistite, nosite nepremočljive rokavice.

• Zdravila za zdravljenje raka lahko povzročijo resne neželene učinke, zato lahko

• Ureznine, odrgnine in razpokano kožo nemudoma umijte s toplo vodo zdravnik začasno prekine ali popolnoma preneha z zdravljenjem. 1

in milom. Nato na predel nanesite antiseptično mazilo in ga prekrijte s povojem.

Nemudoma obvestite osebnega zdravnika:

• če dobite drisko,

Izogibajte se bacilom

• če se pojavi povišana telesna temperatura,

• Ne približujte se ljudem z nalezljivimi boleznimi, kot so gripa, prehladi,

• če imate hude bolečine v predelu trebuha, povišano telesno temperaturo, ošpice ali norice.

če vas trese, vam je slabo, bruhate, imate trd trebuh ali ste napihnjeni

• Izogibajte se množicam.

• če vas boli katera od okončin, če zateka, postaja rdeča, topla,

• če se pojavi hujša krvavitev.

Do kože bodite nežni

Driska

• Pri britju bodite previdni in izogibajte se mokremu britju.

• Če pri hudi driski zdravila ne učinkujejo, lahko ta postane resna. Resna ali

• Uporabljajte nežna mila ter izdelke za umivanje las in telesa.

dolgotrajna driska lahko vodi do izgube tekočin, elektrolitov in/ali vpliva

• Namesto mil raje uporabljajte vodno kremo za kopanje.

na delovanje ledvic.

• Nežno se otrite s suho, gladko brisačo (ne drgnite se z debelimi brisačami).

Nizka koncentracija levkocitov

• Pazite, da vaši bivalni prostori niso prekomerno ogrevani, saj topel in suh zrak lahko kožo izsuši.

• Zdravila za zdravljenje raka lahko včasih znižajo koncentracijo levkocitov v krvi.

• To lahko postane resno, saj se telesu zmanjša sposobnost, da se bori proti okužbam.

• Če imate nizko koncentracijo levkocitov, zdravnik lahko predpiše zdravilo, ki bo vaše telo spodbudilo, da bo proizvedlo več levkocitov.

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Spremembe delovanja jeter

Dodatna pomoč

• Zdravila za zdravljenje raka, kakršno je zdravilo nintedanib, lahko vplivajo tudi na izvide laboratorijskih preiskav jeter. Zdravnik lahko zaradi sprememb delovanja jeter prilagodi vaše zdravljenje. 1

• Društvo pljučnih in alergijskih bolnikov Slovenije: http://www.dpbs.si/

• Društvo onkoloških bolnikov Slovenije: http://www.onkologija.org/

• Ta možnost je eden od razlogov, zakaj bo zdravnik predpisal redne krvne preiskave; s tem bo namreč spremljal delovanje vaših jeter.

Pokličite svojega osebnega zdravnika, če imate katerega od naslednjih znakov ali težav z jetri:

• vaša koža in oči postajajo rumeni,

• utrujeni ste bolj kot običajno,

• vaš urin je temen ali rjav (barve črnega čaja),

• nenehno vam je slabo in bruhate, čeprav jemljete tablete proti slabosti,

• boli vas na desni strani trebuha,

• krvavite ali opraskate se hitreje kot običajno.

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Viri

1. Vargatef® Navodilo za uporabo 2016.

6. NHS. Chemotherapy-Side Eff ects. Dostopno 11/04/2016 na: http://www.nhs.

2. American Cancer Society. The Goals of Chemotherapy dostopno 11/04/16

uk/Conditions/Chemotherapy/Pages/Side-eff ects.aspx.

na http://www.cancer.org/treatment/treatmentsandsideeff ects/

7. Cancer network: Diarrhea in Cancer Patients. Dostopno 11/04/2016 na: http://

treatmenttypeschemotherapy/index.

www.cancernetwork.com.

3. Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 8. NCCN. Nausea and Vomiting. Dostopno 11/04/2016 na: http://www.nccn.

2008: GLOBOCAN 2008. Int J Cancer. 2010; 127:2893-2917.

org/patients/resources/life_with_cancer/managing_symptoms/preventing_

4. NCCN. Clinical Practice Guidelines in Oncology for Patients. Dostopno nausea.aspx.

11/04/2016 na: http://www.nccn.org/patients/guidelines/nscl/index.html.

9. Cancer Council. Cancer treatment and nausea and vomiting. Dostopno 5. Reck M, Kaiser R, Mellemgaard A, et al. Docetaxel plus nintedanib versus 11/04/2016 na: http://www.cancercouncil.com.au/2710/cancer-information/

docetaxel plus placebo in patients with previously treated non-small-cell lung cancer-treatment/managing-side-eff ects-of-treatment/cancer-treatment-and-cancer (LUME-Lung 1): a phase 3, double-blind, randomised controlled trial.

nausea-and-vomiting/.

Lancet Oncol. 2014;15:143-55.

10. Dostopno 11/04/2016 na: http://www.cdc.gov/cancer/preventinfections/.

SI/VAR/0416/00001

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Kontakti

Ta del naj vam pomaga izpolniti zdravnik, da boste vedeli, koga poklicati in kdaj.

• Koga naj pokličem, če imam vprašanja glede zdravljenja?

Ime: ..............................................................................................................................

E-mail: .........................................................................................................................

Telefonska številka: ................................................................................................

• Koga naj pokličem v nujnih primerih?

Ime: ..............................................................................................................................

Moj dnevnik za zdravilo nintedanib

Telefonska številka: ................................................................................................

• So na voljo še kakšni drugi koristni kontakti?

Dnevnik vam bo pomagal spremljati potek

........................................................................................................................................

zdravljenja

........................................................................................................................................

........................................................................................................................................

• Dnevnik, katerega boste vsako jutro in večer izpolnjevali le nekaj

........................................................................................................................................

minut, vam bo omogočil, da boste zdravilo jemali ob pravem času, ter

........................................................................................................................................

spremljali svoje počutje med zdravljenjem.

........................................................................................................................................

• Če boste dnevnik redno nosili na vse preglede, bo zdravnik lahko

........................................................................................................................................

presodil, kako napredujete z zdravljenjem, in poskrbel za vas na

........................................................................................................................................

najboljši možni način.

........................................................................................................................................

........................................................................................................................................

24





Moj opomnik za preglede

• Tu vpisujete svoje preglede, da si boste lažje zapomnili čas in datum.

Kaj moram prinesti

Kaj se je spremenilo od

Vrsta pregleda

Dan in datum

Čas

Pri kom

Kje

s seboj

zadnjega pregleda

26





Druga zdravila

• Tu vpisujete vse pomembne informacije glede sprememb pri zdravilih, ki ji že jemljete, in glede novih zdravil, ki jih morate začeti jemati.

Kako vzamem zdravilo

Kdaj?

Kako pogosto?

(npr. zjutraj

Kako?

Ime zdravila

Proti čemu je?

(npr. 2-krat na dan)

ali zvečer)

(npr. pri jedi)

Drugo

28





1. dan

Datum:

Danes se dobim z zdravniškim

timom in prejmem kemoterapijo.*

Kako naj uporabljam Moj dnevnik za zdravilo

Danes ne vzamem zdravila VARGATEF®.

nintedanib?

Izpolnjevanje dnevnika je odličen pripomoček, ki vam pomaga

* Pri zdravljenju z zdravilom nintedanib in kemoterapijo, se kemoterapijo običajno prejme na 21 dni, vendar pa je interval lahko tudi malce daljši ali krajši. Vaš zdravstveni tim vam bo pomagal zdravilo jemati pravočasno.

določiti datum naslednje kemoterapije. Datuma in ure ne pozabite vpisati v “Moj opomnik Vanj lahko zapisujete tudi stvari, o katerih bi se želeli posvetovati z pregledov”.

zdravnikom na naslednjem pregledu.

Primer

2. dan

Datum:

Datum: 22. Feb

Danes zjutraj

Danes zvečer

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kdaj sem vzel-a zdravilo?

7.30

19.45

Kako se počutim danes?

Kako se počutim danes?

__________________________________________________________________

Po včerajšnji kemoterapiji sem utrujen-a, vendar vesel-a, da lahko __________________________________________________________________

začnem z novim zdravljenjem, pripravljen-a sem na boj _____________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Morebitna vprašanja za zdravnika?

Morebitna vprašanja za zdravnika

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

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30



3. dan

Datum:

5. dan

Datum:

Danes zjutraj

Danes zvečer

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kdaj sem vzel-a zdravilo?

Kako se počutim danes?

Kako se počutim danes?

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Morebitna vprašanja za zdravnika

Morebitna vprašanja za zdravnika _____________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

4. dan

Datum:

6. dan

Datum:

Danes zjutraj

Danes zvečer

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kdaj sem vzel-a zdravilo?

Kako se počutim danes?

Kako se počutim danes?

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Morebitna vprašanja za zdravnika _____________________________________

Morebitna vprašanja za zdravnika _____________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

32



7. dan

Datum:

9. dan

Datum:

Danes zjutraj

Danes zvečer

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kdaj sem vzel-a zdravilo?

Kako se počutim danes?

Kako se počutim danes?

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Morebitna vprašanja za zdravnika

Morebitna vprašanja za zdravnika _____________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

8. dan

Datum:

10. dan

Datum:

Danes zjutraj

Danes zvečer

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kdaj sem vzel-a zdravilo?

Kako se počutim danes?

Kako se počutim danes?

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Morebitna vprašanja za zdravnika _____________________________________

Morebitna vprašanja za zdravnika _____________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

34



11. dan

Datum:

13. dan

Datum:

Danes zjutraj

Danes zvečer

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kdaj sem vzel-a zdravilo?

Kako se počutim danes?

Kako se počutim danes?

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Morebitna vprašanja za zdravnika

Morebitna vprašanja za zdravnika _____________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

12. dan

Datum:

14. dan

Datum:

Danes zjutraj

Danes zvečer

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kdaj sem vzel-a zdravilo?

Kako se počutim danes?

Kako se počutim danes?

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Morebitna vprašanja za zdravnika _____________________________________

Morebitna vprašanja za zdravnika _____________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

36



15. dan

Datum:

17. dan

Datum:

Danes zjutraj

Danes zvečer

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kdaj sem vzel-a zdravilo?

Kako se počutim danes?

Kako se počutim danes?

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Morebitna vprašanja za zdravnika

Morebitna vprašanja za zdravnika _____________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

16. dan

Datum:

18. dan

Datum:

Danes zjutraj

Danes zvečer

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kdaj sem vzel-a zdravilo?

Kako se počutim danes?

Kako se počutim danes?

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Morebitna vprašanja za zdravnika _____________________________________

Morebitna vprašanja za zdravnika _____________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

38





19. dan

Datum:

21. dan

Datum:

Danes zjutraj

Danes zvečer

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kdaj sem vzel-a zdravilo?

Kako se počutim danes?

Kako se počutim danes?

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Morebitna vprašanja za zdravnika

Morebitna vprašanja za zdravnika _____________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

20. dan

Datum:

__________________________________________________________________

Danes zjutraj

Danes zvečer

Kdaj sem vzel-a zdravilo?

Kako se počutim danes?

22. dan

Datum:

__________________________________________________________________

__________________________________________________________________

__________________________________________________________________

Danes se dobim z zdravniškim

__________________________________________________________________

timom in prejmem kemoterapijo.*

Morebitna vprašanja za zdravnika _____________________________________

__________________________________________________________________

Danes ne vzamem zdravila VARGATEF®.

__________________________________________________________________

__________________________________________________________________

* Pri zdravljenju z zdravilom VARGATEF® in kemoterapijo, se kemoterapijo običajno prejme na __________________________________________________________________

21 dni, vendar pa je interval lahko tudi malce daljši ali krajši. Vaš zdravstveni tim vam bo pomagal __________________________________________________________________

določiti datum naslednje kemoterapije. Datuma in ure ne pozabite vpisati v “Moj opomnik pregledov”.

40





Druge informacije, ki mi jih je dal zdravnik

Moji zapiski

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42



MOJ PRIROČNIK IN DNEVNIK ZA ZDRAVLJENJE Z NINTEDANIBOM

Avtor: Boehringer Ingelheim

Strokovna recenzija: Prof. dr. Tanja Čufer, dr. med. in Mag. Mojca Unk, dr. med.

Oblikovanje: Greta Avsec s.p.

Prevod in lektoriranje: ARTIKULA, Nina Šega, s.p.

Izdala: Onkološki Inštitut Ljubljana in Klinika Golnik Tisk: Greta Avsec s.p.

Izdajo omogočil: Boehringer Ingelheim RCV GmbH&CoKG, Podružnica v Ljubljani, Šlandrova 4b, 1231 Ljubljana-Črnuče Naklada: 100 kom

Leto izdaje: 2016

INT/2016/3