Medical Imaging and Radiotherapy Journal (MIRTJ) 39 (Suppl. 1) 29
Medical Imaging and Radiotherapy Journal (MIRTJ) 39 (Suppl. 1)
MR STRES PERFUZIJA SRCA V UKC MARIBOR
MR CARDIAC STRESS PERFUSION AT THE UKC MARIBOR
Benjamin Švec, Teja Štih
Univerzitetni klinični center Maribor, Radiološki oddelek, Ljubljanska ulica 5, 2000 Maribor, Slovenija / 
University medical centre Maribor, Department of Radiology, Ljubljanska ulica 5, 2000 Maribor, Slovenia
Korespondenca / Corresponding author: bsvec12@gmail.com
Prejeto/Recived: 18. 2. 2022
Sprejeto/Accepted: 10. 3. 2022
IZVLEČEK
Uvod in namen: Namen prispevka je predstaviti protokol 
MR (angl. magnetic resonance) stres perfuzijo srca in opisati 
pomembnost preiskave pri pacientih z obolenji koronarnega 
ožilja. MR stresna perfuzija srca je neinvazivna slikovna 
metoda, s katero natančno ocenimo miokard, saj lahko dobro 
ločimo ishemične in neishemične spremembe na srčni mišici.
Metode: Pri 42-letnem pacientu z bolečinami v prsnem košu 
in mejno pozitivnim izvidom obremenitvenega testiranja pri 
kardiologu smo izvedli  MR stres perfuzijo srca. Po opravljeni 
MR stres perfuzijski preiskavi srca so pacientu izvedli še 
koronarografi jo z vstavitvijo stenta v RCA (angl. right coronary 
artery). Magnetno-resonančno preiskavo srca smo opravili na 
MR aparatu Siemens Magnetom Sola 1,5 T. Za obremenitev 
srca med preiskavo smo uporabili zdravilo Regadenoson 
(Rapiscan), ki ga apliciramo v veno. 
Rezultati: Koronarografska preiskava je pokazala 96-odstotno 
stenozo RCA proksimalno. Stresna perfuzija je bila pozitivna, 
saj so bili prisotni perfuzijski defekti v celotni spodnji steni 
miokarda tako med obremenitvijo srca kot v mirovanju in na 
slikah poznega barvanja (angl. late gadolinium enhacement 
– LGE). 
Zaključek: V univerzitetnem kliničnem centru Maribor je stres 
perfuzija srca pogosta in pomembna preiskava pri zdravljenju 
in obravnavi pacientov, ki imajo težave s koronarnimi obolenji.
Ključne besede: magnetna resonanca, stres perfuzija, 
regadenoson, adenozin, koronarna bolezen srca.
ABSTRACT
Introduction and purpose: The purpose of this article is to 
present the magnetic resonance (MR) protocol of cardiac 
perfusion and to describe the importance of the study in 
patients with coronary artery disease. MR Stress perfusion of 
the heart is a noninvasive imaging modality that accurately 
assesses the myocardium because we can discriminate 
well between ischemic and nonischemic changes in the 
myocardium.
Methods: In a 42-year-old patient with chest pain and a 
borderline positive stress test by a cardiologist, we performed 
MR stress perfusion of the heart. After MR stress perfusion of the 
heart, the patient underwent coronary angiography, during 
which a stent was placed in the RCA (right coronary artery). 
Magnetic resonance imaging of the heart was performed on 
a Siemens Magnet Sola 1.5 T MR machine. To stress the heart 
during the examination, we used Regadenoson (Rapiscan) 
administered intravenously.
Results: Coronary angiographic examination showed 96% RCA 
stenosis proximally. Stress perfusion was positive, as perfusion 
defects were seen throughout the inferior myocardial wall 
during cardiac stress as well as at rest and in late gadolinium 
enhancement (LGE) images.
Conclusions: At the University Medical Centre Maribor, cardiac 
stress perfusion is common and an important investigation 
in the treatment and care of patients with coronary artery 
disease problems.
Keywords: magnetic resonance imaging, stress perfusion, 
regadenoson, adenosine, coronary artery disease.
30 Medical Imaging and Radiotherapy Journal (MIRTJ) 39 (Suppl. 1)
Medical Imaging and Radiotherapy Journal (MIRTJ) 39 (Suppl. 1)
LITERATURA / REFERENCES
McRobbie, D. W. et al. (2006) MRI From Picture to Proton. Second. 
Cambridge: Cambridge University Press. doi: 10.1017/
CBO9780511545405.
Netter, F. H. (2019) Atlas of human anatomy. Seventh. 
Philadelphia, PA: Elsevier.
Rizzello, V. et al. (2006) ‘Long term prognostic value of 
myocardial viability and ischaemia during dobutamine 
stress echocardiography in patients with ischaemic 
cardiomyopathy undergoing coronary revascularisation’, 
Heart, 92(2), pp. 239–244. doi: 10.1136/hrt.2004.055798.
Leong, D. P., De Pasquale, C. G. and Selvanayagam, J. B. 
(2010) ‘Heart failure with normal ejection fraction: The 
complementary roles of echocardiography and CMR 
imaging’, JACC: Cardiovascular Imaging, 3(4), pp. 409–420. 
doi: 10.1016/j.jcmg.2009.12.011.
Gilutz, H., Shindel, S. and Shoham-Vardi, I. (2019) ‘Adherence 
to NSTEMI Guidelines in the Emergency Department: 
Regression to Reality’, Critical Pathways in Cardiology, 18(1), 
pp. 40–46. doi: 10.1097/HPC.0000000000000165.
Boztosun, B. et al. (2008) ‘The longest documented left main 
coronary artery’, International Journal of Cardiology, 126(1), 
pp. 17–18. doi: 10.1016/j.ijcard.2006.12.088.